Results 301 to 310 of about 1,259,046 (413)
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu+13 more
wiley +1 more source
Exploring the peroxidase-like activity of 4Fe-Ni-B nanoparticles for analytical sensing. [PDF]
Deng SH, Ma YZ, Han YF, Zhou Q, Fu WS.
europepmc +1 more source
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang+10 more
wiley +1 more source
The fungus among us: Rice blast fungus blocks ROS production and starch breakdown to disrupt host resistance. [PDF]
Howe V.
europepmc +1 more source
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo+16 more
wiley +1 more source
Linking the Metabolic Activity of Plastic-Degrading Fungi to Their Taxonomy and Evolution. [PDF]
Ekanayaka AH+8 more
europepmc +1 more source
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang+11 more
wiley +1 more source