The Role of Salicylic Acid in Activating Plant Stress Responses-Results of the Past Decade and Future Perspectives. [PDF]
Decsi K+3 more
europepmc +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan+12 more
wiley +1 more source
Scrutinizing the evidence of anthracene toxicity on adrenergic receptor beta-2 and its bioremediation by fungal manganese peroxidase via in silico approaches. [PDF]
Naveed M+8 more
europepmc +1 more source
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao+6 more
wiley +1 more source
A G-type lectin receptor-like kinase TaSRLK confers wheat resistance to stripe rust by regulating the reactive oxygen species signaling pathway. [PDF]
Niu E+6 more
europepmc +1 more source
Purification and Iodinating Activity of Hog Thyroid Peroxidase
Myer L. Coval, Alvin Taurog
openalex +1 more source
A multi‐functional photo‐enzymatic nanoreactor HRP@Fe‐NU‐1003 is developed through co‐immobilization of horseradish peroxidase and FeCl2 on a photosensitive metal–organic frameworks NU‐1003. This material showcases remarkable sensitivity and efficacy in both detecting and subsequently photo‐degrading chloramphenicol residues in food products.
Lu Ran+5 more
wiley +1 more source
Lignin-Degrading Enzymes and the Potential of <i>Pseudomonas putida</i> as a Cell Factory for Lignin Degradation and Valorization. [PDF]
Zhou Q, Fransen A, de Winde H.
europepmc +1 more source
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi+20 more
wiley +1 more source
Thyroid peroxidase antibodies and their role in predicting outcomes in Graves' disease treatment. [PDF]
Gewert K+3 more
europepmc +1 more source