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Synthetic peroxides as antimalarials

Medicinal Research Reviews, 2004
AbstractThe discovery of artemisinin in 1971 initiated a new era in antimalarial chemotherapy. Although the clinically useful semisynthetic artemisinin derivatives are rapid acting and potent antimalarial drugs, they have short half‐lives and must be administered over a period of 5–7 days, leading to noncompliance and recrudescence.
Yuanqing Tang   +2 more
openaire   +5 more sources

Lipid Peroxidation

1997
Publisher Summary This chapter presents the fundamental characteristics of oxygen radical-induced lipid peroxidation (LP) as they relate to the pathophysiology of focal and global cerebral ischemia and subarachnoid hemorrhage (SAH). There is extensive biochemical, physiological, and pharmacological evidence in support of an important role of LP in ...
openaire   +3 more sources

Rational Design of an α-Ketoamide-Based Near-Infrared Fluorescent Probe Specific for Hydrogen Peroxide in Living Systems.

Analytical Chemistry, 2016
Hydrogen peroxide, an important biomolecule, receives earnest attention because of its physiological and pathological functions. In this Article, we present the rational design, characterization, and biological application of a mitochondria-targetable ...
Xilei Xie   +7 more
semanticscholar   +1 more source

Atomically dispersed antimony on carbon nitride for the artificial photosynthesis of hydrogen peroxide

Nature Catalysis, 2021
Zhenyuan Teng   +11 more
semanticscholar   +1 more source

Ascorbate peroxidase – a hydrogen peroxide‐scavenging enzyme in plants

, 1992
Ascorbate peroxidase is a hydrogen peroxide-scavenging enzyme that is specific to plants and algae and is indispensable to protect chloroplasts and other cell constituents from damage by hydrogen peroxide and hydroxyl radicals produced from it.
K. Asada
semanticscholar   +1 more source

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro.

Science, 1988
Exposure of Escherichia coli to low concentrations of hydrogen peroxide results in DNA damage that causes mutagenesis and kills the bacteria, whereas higher concentrations of peroxide reduce the amount of such damage.
J. Imlay, S. M. Chin, S. Linn
semanticscholar   +1 more source

Actinyl Peroxide Nanospheres

Angewandte Chemie, 2005
[*] Prof. P. C. Burns, K.-A. Kubatko, G. SigmonDepartment of Civil Engineering and Geological SciencesUniversity of Notre Dame156 Fitzpatrick Hall, Notre Dame, IN 46556 (USA)Fax: ( +1)574-631-9236E-mail: pburns@nd.eduProf.Dr. B. J. Fryer, J. E. GagnonGreat Lakes Institute for Environmental ResearchUniversity of WindsorWindsor, Ontario N9B 3P4 (Canada ...
Joel E. Gagnon   +6 more
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Coulometric microdetermination of peroxides—II☆Organic peroxides

Talanta, 1973
An iodometric method for the rapid microdetermination of organic peroxides, utilizing electrochemical reduction in the iodine-iodide system, has been developed. After complete reaction between peroxide and iodide in an acidic semi-aqueous medium the iodine produced is reduced at a rotating platinum electrode, at constant potential.
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PEROXIDE EXPLOSIVES

2006
The sensitivity and/or stability of an energetic materials is often assessed by its weakest bond-its trigger linkage (Table 1). This is generally the C-NO2 in nitrated explosives. In peroxides it is the -O-O- bond. © 2006 Springer.
Oxley, Jimmie, Smith, James
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Coulometric microdetermination of peroxides—I. Hydrogen peroxide

Talanta, 1973
An electroanalytical method, based on controlled-potential coulometry in the iodine-iodide system, has been developed for determination of small amounts of hydrogen peroxide. The sample is added to an electrolyte containing an acid solution of iodide and the iodine, which is produced rapidly, is reduced at a rotating platinum electrode.
openaire   +3 more sources

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