Results 141 to 150 of about 248,501 (390)

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Peroxisome Proliferator-Activated Receptor and Retinoic X Receptor in Alcoholic Liver Disease

PPAR Research, 2009
A growing number of new studies demonstrate that nuclear receptors are involved in the development of alcoholic liver disease (ALD). Ethanol metabolism and RXR/PPAR functions are tightly interconnected in the liver.
Tommaso Mello, Simone Polvani, Andrea Galli   +2 more
doaj   +1 more source

Supplementary Figure 5 from Role of Peroxisome Proliferator-Activated Receptor-γ and Its Coactivator DRIP205 in Cellular Responses to CDDO (RTA-401) in Acute Myelogenous Leukemia [PDF]

, 2023
Twee Tsao, Steven M. Kornblau, Stephen Safe, Julie C. Watt, Vivian Ruvolo, Wenjing Chen, Yihua Qiu, Kevin R. Coombes, Zhenlin Ju, Maen Abdelrahim, Wendy Schober, Xiaoyang Ling, Dimitris Kardassis, Colin Meyer, Aaron D. Schimmer, Hagop M. Kantarjian, Michael Andreeff, Marina Konopleva   +17 more
openalex   +1 more source

Descriptive Epidemiology From the Myhre Syndrome Foundation Registry: The Value of Self‐Reported Data

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young, Armelle Pindon, Maggie R. Brand, Kate Wears, Katherine H. Young, Alyssa Mendel, Michael J. Lyons   +6 more
wiley   +1 more source

An Asymmetric Synthesis of PPAR-? Agonist Navaglitazar from (+)-Methyl (2S,3R)-3-(4-methoxyphenyl)glycidate

CHIMIA, 2006
An asymmetric synthesis of navaglitazar, a peroxisome proliferator activated receptor (PPAR) ? agonist, from commercially available (+)-methyl (2S,3R)-3-(4-methoxyphenyl)glycidate, is described. The new synthesis features high overall yield, low
John R. Rizzo, Tony Y. Zhang
doaj   +1 more source

Role of Peroxisome Proliferator-Activated Receptor γ in Ocular Diseases

Journal of Ophthalmology, 2015
Peroxisome proliferator-activated receptor γ (PPAR γ), a member of the nuclear receptor superfamily, is a ligand-activated transcription factor that plays an important role in the control of a variety of physiological processes.
Su Zhang, Hongwei Gu, Nan Hu
doaj   +1 more source

Role of Peroxisome Proliferator-Activated Receptor-γ in Vascular Inflammation

International Journal of Vascular Medicine, 2012
Vascular inflammation plays a crucial role in atherosclerosis, and its regulation is important to prevent cerebrovascular and coronary artery disease.
Kousei Ohshima, Masaki Mogi, Masatsugu Horiuchi   +2 more
doaj   +1 more source

O02 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA FUNCTIONS AS AN ANTIBACTERIAL FACTOR [PDF]

, 2007
Laurent Peyrin‐Biroulet, Xavier Thuru, Cécile Vignal, Laurent Dubuquoy, Emilie Mérour, Edmone Erdual, Christel Neut, Philippe Chavatte, Arlette Darfeuille–Michaud, J F. Colombel, Pierre Desreumaux, Mathias Chamaillard   +11 more
openalex   +1 more source

Atorvastatin protects against postoperative neurocognitive disorder via a peroxisome proliferator-activated receptor-gamma signaling pathway in mice [PDF]

, 2020
Yinan Yang, Changwei Wei, Liu Jin-hu, Danxu Ma, Chao Xiong, Dandan Lin, Anshi Wu   +6 more
openalex   +1 more source

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source