Results 311 to 320 of about 84,481 (342)
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Effect of peroxynitrite on glutaredoxin
Human & Experimental Toxicology, 2001Glutaredoxin is an important enzyme in thiol homeostasis. As a thioltransferase, it reduces oxidized thiols. It also has dehydroascorbate reductase (DHAR) activity to reduce dehydroascorbate (DHA) to ascorbic acid. Peroxynitrite (ONOO-) is one of the most active elements of oxidative stress that can be formed wherever nitric oxide and superoxide are ...
Bulgurcuoğlu S +2 more
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Analytical Chemistry, 2017
In this study, the far-red-emitting fluorescence probe 1, containing a rhodamine derivative and a hydrazide reactive group, was developed for peroxynitrite detection and imaging.
Di Wu +6 more
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In this study, the far-red-emitting fluorescence probe 1, containing a rhodamine derivative and a hydrazide reactive group, was developed for peroxynitrite detection and imaging.
Di Wu +6 more
semanticscholar +1 more source
Advanced Healthcare Materials, 2018
Peroxynitrite (ONOO‐), a potent biological oxidant, which has a short half‐life in physiological conditions, is related to many diseases. Accurate peroxynitrite determination with superior selectivity and sensitivity is important for understanding ...
Zejing Chen +8 more
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Peroxynitrite (ONOO‐), a potent biological oxidant, which has a short half‐life in physiological conditions, is related to many diseases. Accurate peroxynitrite determination with superior selectivity and sensitivity is important for understanding ...
Zejing Chen +8 more
semanticscholar +1 more source
Provoking Neuroprotection by Peroxynitrite
Current Pharmaceutical Design, 2004Peroxynitrite, the product of the reaction between nitric oxide and superoxide, is spontaneouly formed within most mammalian cells under physiological conditions. Initial work addressing the pathophysiology of peroxynitrite afforded the generally accepted notion that this compound would be the long-term neurotoxic nitric oxide-derivative. However, over
Angeles Almeida +2 more
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Peroxynitrite and fibrinolytic system—The effects of peroxynitrite on t-PA-induced plasmin activity
International Journal of Biological Macromolecules, 2015The aim of the present study was the investigation of peroxynitrite (ONOO(-)) effects on fibrinolysis in vitro and in silico. The exposure of human plasminogen to ONOO(-) (10-1000μM) resulted in a decrease of t-PA-induced amidolytic activity of plasmin; the inhibitory effect was associated with the increasing level of 3-nitrotyrosine in plasminogen ...
Pawel Nowak +2 more
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Peroxynitrite Scavenging Activity of Indole Derivatives: Interaction of Indoles with Peroxynitrite
Journal of Medicinal Food, 2004One of the products of nitrogen-derived free radicals, peroxynitrite (ONOO(-)), is formed by the reaction of superoxide anion (O(2)(*-)) with nitric oxide (NO). ONOO(-) can cause damage to proteins and DNA through nitration. In particular, proteins and their constituent amino acids have been proven to be extremely sensitive to ONOO(-).
Min-Sun Kim +10 more
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[23] Oxidative chemistry of peroxynitrite
1994Publisher Summary Nitric oxide (.NO) is an important and largely unrecognized mediator of oxygen radical injury because it contains an unpaired electron that readily combines with many free radicals. Endothelium and neurons produce nitric oxide as an intercellular messenger, which has important roles in vasoregulation and synaptic plasticity.
Jun Chen +3 more
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Catalytic scavenging of peroxynitrite by catalase
Journal of Inorganic Biochemistry, 2009Peroxynitrite (ONOO(-)/ONOOH), the product of the diffusion controlled reaction between nitric oxide (*NO) and superoxide anion (O(2)(-)*), is a strong oxidizing and nitrating agent. Several heme proteins react rapidly with peroxynitrite, some of them catalyze its decomposition.
Joanna Didik, Lidia Gebicka
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Helvetica Chimica Acta, 2000
Peroxynitrite (ONOO−, oxoperoxonitrate(1−)), an isomer of nitrate that oxidizes and nitrates biomolecules, is likely to be formed in vivo from the reaction of superoxide with nitrogen monoxide. To determine whether flavonoids scavenge peroxynitrite as postulated in the literature, we studied the reactions of peroxynitrite with phenol, hydroquinone ...
Sonja Tibi, Willem H. Koppenol
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Peroxynitrite (ONOO−, oxoperoxonitrate(1−)), an isomer of nitrate that oxidizes and nitrates biomolecules, is likely to be formed in vivo from the reaction of superoxide with nitrogen monoxide. To determine whether flavonoids scavenge peroxynitrite as postulated in the literature, we studied the reactions of peroxynitrite with phenol, hydroquinone ...
Sonja Tibi, Willem H. Koppenol
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Rearrangement of peroxynitrite esters
Journal of the Chemical Society, Chemical Communications, 1977AbstractDas Hydroperoxyprogesteron (I) reagiert mit Nitrosylchlorid in Pyridin bei 0°C zum Nitrat (II).
Derek H. R. Barton +3 more
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