Results 111 to 120 of about 52,578 (283)
The dynamic trio: The relationship between passion, perseverance and job satisfaction
TourismThis work aims to enhance the understanding of the dynamic relationship between passion, perseverance and job satisfaction among tour guides, recognizing the interconnected nature of these elements and their impact on tourism experience.
Mitja Gorenak +2 more
doaj +1 more source
HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery, 2020 openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
International Journal of Educational PsychologyGrit, the passion for achieving long-term goals, has been conceived as a two-dimensional construct (Consistency of interest and Perseverance of effort). The construct is well known for its easy measurement and its relationship with performance, including
Miguel Eduardo Uribe-Moreno +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
perseverance knows no boundaries [PDF]
perseverance knows no boundaries is an acrostic poem celebrating empowerment, resilience, and self ...
Peñaloza-Rayo, Amaris
core +1 more source
EDUCATION OF VOLITIVE QUALITIES IN PRIMARY SCHOOLSTUDENTS
Ra Ximhai, 2016 The paper aims to present the results of the application of the methodology developed by the author, as a scientific result of his doctoral studies, aimed at the education of volitional qualities self control and perseverance, respect to teaching in ...
Pablo Ángel Martínez-Morales
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
A Self-Confident Profile: An Analysis of the Novel The Old Man and the Sea
Journal of Language and LiteratureThis analysis examines Ernest Hemingway's classic novel, The Old Man and the Sea, through the lens of the self-confident profile portrayed by the protagonist, Santiago.
Majid Wajdi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source