Results 101 to 110 of about 52,578 (283)
Perseverance in the religious life
“I wonder what it is that makes one person push on in the face of difficulty and makes someone else crumble in helplessness.” – Fred Rogers In the movie Rocky IV (1985), heavyweight boxer Rocky Balboa reveals in a heart-to-heart talk
Howard-Snyder, Daniel +1 more
core +3 more sources
The changes in adolescents’ visions for the future are important to adolescents’ developmental trajectories, motivation, and educational outcomes, yet understudied.
Shimin Zhu, Chongzeng Bi
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Personality and Response to the Financial Crisis [PDF]
In a previous study, we found the family of personality traits known as conscientiousness to be associated in cross-sectional analyses with both lifetime earnings and wealth.
Angela Duckworth, David Weir
core
The Maze Test: A Computer Tool for Testing Perseverance
Wojciech Styk,1 Waldemar Klinkosz2 1Institute of Psychology, The John Paul II Catholic University of Lublin, Lublin, Poland; 2Institute of Psychology, Cardinal Stefan Wyszynski University in Warsaw, Warsaw, PolandCorrespondence: Wojciech StykInstitute of
Styk W, Klinkosz W
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
This paper proposes a model of the dynamics formation process of the value of perseverance in mathematical problems solving, the one is structured in two dimensions: the cognitive-solver and the affective-solver.
Isabel Alonso Berenguer +2 more
doaj
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source

