Results 131 to 140 of about 267,335 (315)

Can Resilience Be Our Teacher Super-power?

open access: yes, 2019
Teaching is courageous work. Today\u27s teachers face heavy workloads and growing emotional responsibilities as K-12 students and families face complicated hurdles and issues such as mental health issues, immigration, and natural disasters.
Hughes, Michelle C, Dr.
core  

Spinoza, Baruch [PDF]

open access: yes, 2013
Baruch, or Benedictus, Spinoza (1632–77) is the author of works, especially the Ethics and the Theological-Political Treatise, that are a major source of the ideas of the European Enlightenment.
LeBuffe, Michael
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Les étudiants préfèrent Facebook

open access: yesDistances et Médiations des Savoirs, 2014
This paper presents the results of a study of the methods of learning and the use of technologies by Quebec university students, which shows that they are little attracted by distance learning and online learning. Hypothesizing that their perceptions may
Patrick Guillemet
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Assessment and the self: academic practice and character attributes [PDF]

open access: yes, 2015
A case is made for how, within higher education, we might make use of the relationship that exists between students’ academic practices and outputs, and their character attributes such as open-mindedness, enthusiasm and perseverance.
Hanscomb, Stuart
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

HUBUNGAN ANTARA GROWTH MINDSET DENGAN GRIT PADA REMAJA GENERASI Z [PDF]

open access: yes
Gen Z is analogous as strawberry generation because they assumed to be creative, skilled, and critical, but are vulnerable to destruction or lack resilience when facing competition or obstacles.
Kharisma, Adelia Nur
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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