Results 61 to 70 of about 52,578 (283)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Remote SensingThe NASA Mars 2020 Mission Perseverance rover has conducted a four-Martian-year scientific campaign in the Jezero western fan, a typical fluvial–deltaic–lacustrine system on Mars. Equipped with the Planetary Instrument for X-ray Lithochemistry (PIXL) and
Wenbo Huang +7 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Development and validation of multi-dimensional scale of grit
Cogent Psychology, 2021 Positive psychology nurtures the potent qualities of individuals and aids them in carving a niche for themselves. Based on this theoretical foundation, a non-cognitive trait-like grit plays an imperative role in attaining high achievement.
Sabah Singh, Surekha Chukkali
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The civil position of Alexandru V. Boldur
Tyragetia, 2017 The article is devoted to the civil position of the Bessarabian historian Alexandru Boldur in certain life circumstances. The author on the basis of archival materials presents and analyzes a concrete example - two appeals, the first to the Bucharest ...
Ioan Opriş
doaj
Prospective Teachers’ Self-Regulation: The History of Mathematics as a Tool for Perseverance
Education SciencesThe present study investigated the effect of improving prospective teachers’ self-regulation to teach mathematics at primary education through the mathematical courses they attended at a pedagogical department.
Rita Panaoura
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Fariya Naseem: Perseverance pays
, 2021 Inspired by Max Adam’s original work, Unquiet Women, through this series Dr Hafsa Ahmed aims to share narratives of remarkable women who immigrated to New Zealand. These stories are rarely told, but each one is unique.
Ahmed, Hafsa
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source