Results 1 to 10 of about 583,154 (298)
Journal of Postsecondary Student Success, 2022 Addressing labor shortages within nursing and allied health professions, which have been exacerbated by the COVID-19 pandemic, requires increasing persistence and equity among community college students pursuing these fields.
Ross O'Hara, Betsy Sparrow, Lois Joy
doaj +1 more source
mSystems, 2021 Accurate and timely functional genome annotation is essential for translating basic pathogen research into clinically impactful advances. Here, through literature curation and structure-function inference, we systematically update the functional genome ...
Samuel J. Modlin +10 more
doaj +1 more source
STAR Protocols, 2023 Summary: Here, we present a protocol for setting three spectral flow cytometry panels for the characterization of human unconventional CD8+NKG2A/C+ T cells as well as other T and natural killer cell subsets. We describe steps for standardizing, preparing,
Aurelio Orta-Resendiz +6 more
doaj +1 more source
NK-B cell cross talk induces CXCR5 expression on natural killer cells
iScience, 2021 Summary: B cell follicles (BCFs) in lymph nodes (LNs) are generally exempt of CD8+ T and NK cells. African green monkeys (AGMs), a natural host of simian immunodeficiency virus (SIV), display NK cell-mediated viral control in BCF.
Philippe Rascle +10 more
doaj +1 more source
eLife, 2020 This study assembles DNA adenine methylomes for 93 Mycobacterium tuberculosis complex (MTBC) isolates from seven lineages paired with fully-annotated, finished, de novo assembled genomes. Integrative analysis yielded four key results.
Samuel J Modlin +9 more
doaj +1 more source
Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells
mBio, 2017 Bacterial persisters are phenotypic variants that survive antibiotic treatment in a dormant state and can be formed by multiple pathways. We recently proposed that the second messenger (p)ppGpp drives Escherichia coli persister formation through protease
Alexander Harms +4 more
doaj +1 more source
MicrobiologyOpen, 2020 Antibiotic‐tolerant persisters are often implicated in treatment failure of chronic and relapsing bacterial infections, but the underlying molecular mechanisms have remained elusive.
Cinzia Fino +5 more
doaj +1 more source
mBio, 2022 Pyrazinamide (PZA) plays a crucial role in first-line tuberculosis drug therapy. Unlike other antimicrobial agents, PZA is active against Mycobacterium tuberculosis only at low pH. The basis for this conditional drug susceptibility remains undefined.
Joshua M. Thiede +8 more
doaj +1 more source
HipA-Mediated Phosphorylation of SeqA Does not Affect Replication Initiation in Escherichia coli
Frontiers in Microbiology, 2018 The SeqA protein of Escherichia coli is required to prevent immediate re-initiation of chromosome replication from oriC. The SeqA protein is phosphorylated at the serine-36 (Ser36) residue by the HipA kinase.
Leise Riber +4 more
doaj +1 more source
Serine-Threonine Kinases Encoded by Split
mBio, 2019 Type II toxin-antitoxin (TA) modules encode a stable toxin that inhibits cell growth and an unstable protein antitoxin that neutralizes the toxin by direct protein-protein contact.
Stine Vang Nielsen +7 more
doaj +1 more source