Results 21 to 30 of about 983,813 (313)
We ask whether mortality from historical pandemics has any predictive content for mortality in the Covid-19 pandemic. We find strong persistence in public health performance. Places that performed worse in terms of mortality in the 1918 influenza pandemic also have higher Covid-19 mortality today.
Peter Z. Lin, Christopher M. Meissner
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PERSISTENCE IN CONVERGENCE [PDF]
In this paper, we examine the convergence hypothesis using a long memory framework that allows for structural breaks and does not rely on a benchmark country. We find that even though the long memory framework of analysis is much richer than the simple I(1)/I(0) alternative, a simple absolute divergence and rapid convergence dichotomy produced by the ...
Thanasis Stengos, M. Ege Yazgan
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Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells
Bacterial persisters are phenotypic variants that survive antibiotic treatment in a dormant state and can be formed by multiple pathways. We recently proposed that the second messenger (p)ppGpp drives Escherichia coli persister formation through protease
Alexander Harms +4 more
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Antibiotic‐tolerant persisters are often implicated in treatment failure of chronic and relapsing bacterial infections, but the underlying molecular mechanisms have remained elusive.
Cinzia Fino +5 more
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Serine-Threonine Kinases Encoded by Split
Type II toxin-antitoxin (TA) modules encode a stable toxin that inhibits cell growth and an unstable protein antitoxin that neutralizes the toxin by direct protein-protein contact.
Stine Vang Nielsen +7 more
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Pyrazinamide (PZA) plays a crucial role in first-line tuberculosis drug therapy. Unlike other antimicrobial agents, PZA is active against Mycobacterium tuberculosis only at low pH. The basis for this conditional drug susceptibility remains undefined.
Joshua M. Thiede +8 more
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We describe a new methodology for studying persistence of topological features across a family of spaces or point-cloud data sets, called zigzag persistence. Building on classical results about quiver representations, zigzag persistence generalises the highly successful theory of persistent homology and addresses several situations which are not ...
Gunnar E. Carlsson, Vin de Silva
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HipA-Mediated Phosphorylation of SeqA Does not Affect Replication Initiation in Escherichia coli
The SeqA protein of Escherichia coli is required to prevent immediate re-initiation of chromosome replication from oriC. The SeqA protein is phosphorylated at the serine-36 (Ser36) residue by the HipA kinase.
Leise Riber +4 more
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Persistently Finite, Persistently Arithmetic Theories [PDF]
The main result shows that a certain class of theories, the persistently finite, persistently arithmetic theories, have only arithmetic countable models.
Ash, C. J., Millar, T. S.
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Phylogeny Reveals Novel HipA-Homologous Kinase Families and Toxin-Antitoxin Gene Organizations
Bacterial multidrug tolerance and persistence are problems of increasing scientific and medical significance.
Kenn Gerdes +2 more
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