Results 111 to 120 of about 606,469 (298)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Labor-Market Adjustments and the Persistence of Unemployment

, 1995
Joseph E. Stiglitz, Bruce Greenwald
openalex   +1 more source

Apical hypertrophic cardiomyopathy: chest pain and myocardial perfusion defects result from regional diastolic persistence of hyperdynamic cardiac contractility [PDF]

, 2013
Edward R. Stephenson, Pierre Monney, Redha Boubertakh, J. Nackvi, Neha Sekhri, Peter Mills, Andrew Wragg, Anthony Mathur, Steffen E. Petersen, Saidi Mohiddin   +9 more
openalex   +1 more source

Data from: Prioritizing global land protection for population persistence can double the efficiency of habitat protection for reducing mammal extinction risk

, 2023
Nicholas H. Wolff, Piero Visconti, Heini Kujala, Luca Santini, Jelle P. Hilbers, Hugh P. Possingham, James R. Oakleaf, Christina M. Kennedy, Joseph M. Kiesecker, Joseph Fargione, Edward T. Game   +10 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

OP 1.2 – 00157 HIV Silencing and Cell Survival Signatures of HIV-Infected CD4 T Cell Transcriptomes under Antiretroviral Therapy (ART)

Journal of Virus Eradication, 2022
I.C. Clark, P. Mudvari, S. Thaploo, S. Smith, M. Abu-Laban, S.G. Deeks, F.J. Quintana, D.C. Douek, A.R. Abate, E.A. Boritz   +9 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Persistence and adherence in multiple sclerosis patients starting glatiramer acetate treatment: assessment of relationship with care received from multiple disciplines

Patient Preference and Adherence, 2016
Peter Joseph Jongen,1,2 Wim A Lemmens,3 Raymond Hupperts,4 Erwin LJ Hoogervorst,5 Hans M Schrijver,6 Astrid Slettenaar,7 Els L de Schryver,8 Jan Boringa,9 Esther van Noort,10 Rogier Donders3 1Department of Community and Occupational Medicine, University
Jongen PJ, Lemmens WA, Hupperts R, Hoogervorst ELJ, Schrijver HM, Slettenaar A, de Schryver EL, Boringa J, van Noort E, Donders R   +9 more
doaj