Results 61 to 70 of about 583,154 (298)
Persistent URIs Must Be Used To Be Persistent [PDF]
Proceedings of the 25th International Conference Companion on World Wide Web - WWW '16 Companion, 2016 2 pages, 2 figures, accepted for publication at WWW 2016 (poster track)
Shawn M. Jones +2 more
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FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Indeterminism and Persistence [PDF]
Philosophia Naturalis, 2012 This paper aims at bringing together two debates in metaphysics that so far have been kept separate: the debate about determinism vs. indeterminism as de re modality on the one hand, and the debate about persistence on the other hand. Both debates significantly involve talk of things.
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SSRN Electronic Journal, 2001 The recent U.S. expansion has provided employment experience to individuals at tail of the skill distribution. Will these opportunities bestow persistent benefits in the form of greater future employability? Using synthetic cohorts constructed from the CPS, this paper estimates the degree of persistence in cohort-level employment rates in excess of ...
Joshua Hojvat Gallin +1 more
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Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Unravelling the Roles of Bacterial Nanomachines Bistability in Pathogens’ Life Cycle
MicroorganismsBacterial nanomachines represent remarkable feats of evolutionary engineering, showcasing intricate molecular mechanisms that enable bacteria to perform a diverse array of functions essential to persist, thrive, and evolve within ecological and ...
Romain Gory +2 more
doaj +1 more source
Persistent bacterial infections and persister cells
Nature Reviews Microbiology, 2017 Many bacteria can infect and persist inside their hosts for long periods of time. This can be due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective killing by antibiotics. Bacteria can survive antibiotic treatment if they are resistant or tolerant to a drug.
Fisher, RA, Gollan, B, Helaine, S
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FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Re-Defining, Analyzing and Predicting Persistence Using Student Events in Online Learning
Applied Sciences, 2020 In education, several studies have tried to track student persistence (i.e., students’ ability to keep on working on the assigned tasks) using different definitions and self-reported data.
Pedro Manuel Moreno-Marcos +3 more
doaj +1 more source
The Journal of Finance, 1995 ABSTRACTWe explore performance persistence in mutual funds using absolute and relative benchmarks. Our sample, largely free of survivorship bias, indicates that relative risk‐adjusted performance of mutual funds persists; however, persistence is mostly due to funds that lag the S&P 500.
WILLIAM N. GOETZMANN, STEPHEN J. BROWN
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