Results 71 to 80 of about 2,213,349 (340)

Homological Algebra for Persistence Modules

open access: yes, 2020
We develop some aspects of the homological algebra of persistence modules, in both the one-parameter and multi-parameter settings, considered as either sheaves or graded modules. The two theories are different.
Bubenik, Peter, Milicevic, Nikola
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Modulating STDP Balance Impacts the Dendritic Mosaic

open access: yesFrontiers in Computational Neuroscience, 2017
The ability for cortical neurons to adapt their input/output characteristics and information processing capabilities ultimately relies on the interplay between synaptic plasticity, synapse location, and the nonlinear properties of the dendrite ...
Nicolangelo Iannella   +2 more
doaj   +1 more source

Persistent Hospitals

open access: yes, 2022
Global health’s ethic of action is based on the assumption of the absence of functioning health care — i.e. public hospitals, health infrastructure and/or expertise — in spaces where it is most active. Yet, myriads of public hospitals exist or remain in global health’s sites of intervention. This chapter addresses this tension.
Beaudevin, Claire   +2 more
openaire   +3 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Updated Erdman reveals tandem repeat copy number is phase-variable and impacts M. tuberculosis adaptation across evolutionary timescales

open access: yesmSystems
High-quality reference genomes are essential for comparative genomics and accurate genotype-phenotype mapping. Here, we corrected the Mycobacterium tuberculosis Erdman strain reference genome (ErdmanTI) using ultra-deep HiFi sequencing.
Samuel J. Modlin   +6 more
doaj   +1 more source

The high persistence of PFAS is sufficient for their management as a chemical class.

open access: yesEnvironmental Science: Processes & Impacts, 2020
Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic organic substances with diverse structures, properties, uses, bioaccumulation potentials and toxicities.
I. Cousins   +8 more
semanticscholar   +1 more source

Standard To Validate Innovations in Agricultural Testing [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
As global agriculture faces escalating challenges, improved nutrient management procedures are essential for sustainability. Establishing standardized processes to validate and legitimize emerging soil testing technologies is critical for gaining ...
P. Nagel   +4 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Inflation targeting and inflation persistence [PDF]

open access: yes, 2002
This paper argues that the adoption of an inflation target reduces the persistence of inflation. We develop the theoretical literature on inflation persistence by introducing a Taylor rule for monetary policy into a model of persistence and showing ...
Bratsiotis, GJ, Madsen, J, Martin, C
core  

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