Results 131 to 140 of about 23,471,693 (348)

Athlete profiles along grit, sport orientation and sport persistence based on a quantitative research on Hungarian athletes

Frontiers in Sports and Active Living
IntroductionSport persistence, the sustained engagement in sporting activities, is influenced by a combination of intrinsic and extrinsic motivational factors.
Karolina Eszter Kovács
doaj   +1 more source

[Risk factors for persistent diarrhea].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 1996
The current concepts in persistent diarrhoea (PD) are reviewed. 102 patients with acute diarrhoea and 85 with PD are studied. All were less than one year old. Information about age, nutritional status, time of breast feeding, previous episodes of acute and persistent diarrhoea and the previous use of drugs is registered.
E, Sagaro, L E, Rivera, T, Fragoso, N, Gorrín, M, Valdes-Dapena, A, Alonso   +5 more
openaire   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Real-world persistence with antifibrotic treatments: a nationwide study on claims data in France (The REPEAT study)

Respiratory Research
Background Long-term persistence with antifibrotic drugs is crucial to slow disease progression in fibrosing ILDs but is challenging due to adverse events. Large-scale, real-world studies investigating modifiable healthcare system factors associated with
Vincent Cottin, Marie Najean, Elise Arnee, Malamati Voulgaridou, Clementine Dillard, Xavier Ansolabehere, Maxime Doublet, Julien Chollet, Sylvie Leroy, Stephane Jouneau   +9 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Regional Inflation Persistence: Evidence from Italy [PDF]

Regional patterns of inflation persistence have received attention only at a very coarse level of territorial disaggregation, that of EMU member states. However economic disparities within EMU member states are an equally important policy issue.
Guido Ascari, Andrea Vaona
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Testing and Estimating Persistence in Canadian Unemployment. [PDF]

A vital implication of unemployment persistence applies to the Bank of Canada's disinflation policies since it adversely influences unemployment and considerably lengthens recessions.
Curtis J. Eberwein, Ossama Mikhail, Jagdish Handa   +2 more
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

[Persistence factors of Francisella tularensis].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 2006
The study of the persistence potential of 64 F. tularensis strains isolated from different sources was carried out. The wide spread of the antilysozyme, antilactoferrin and anticomplementory activities of F. tularensis were detected. F. tularensis, isolated from ticks and water, were characterized by the highest level of the expression of antilysozyme ...
N V, Sheenkov, E F, Opochinskiĭ, A V, Valyshev, I V, Valysheva, O L, Kartashova, A V, Parshina, O V, Bukharin   +6 more
openaire   +1 more source