Results 41 to 50 of about 23,568 (209)

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao   +4 more
wiley   +1 more source

Vancomycin, Daptomycin, Antistaphylococcal β-Lactam, and Trimethoprim-Sulfamethoxazole Monotherapy and Combination Therapy in the Management of Methicillin-Resistant Staphylococcus aureus: A Network Meta-Analysis

open access: yesFrontiers in Pharmacology, 2022
Objective: The aim was to evaluate the efficacy and safety of vancomycin or daptomycin (VAN/DAP), antistaphylococcal β-lactam (ASBL), trimethoprim-sulfamethoxazole (TMP-SMX), and combination therapy of VAN/DAP + ASBL in the management of methicillin ...
Xiaonan Xu   +6 more
doaj   +1 more source

Active surveillance of drug safety in healthcare data: Sequential monitoring of bacterial and serious urinary tract infection risk in sodium‐glucose cotransporter 2 inhibitor users

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Introduction Active surveillance of adverse events using healthcare data is emerging as complementary to the monitoring of spontaneous reports and stand‐alone pharmacoepidemiologic studies. The risk of urinary tract infections (UTIs) was listed as a special warning for sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) when marketed in Europe
Haoxin Le   +5 more
wiley   +1 more source

Changing characteristics of S. aureus bacteremia caused by PVL-negative, MRSA strain over 11 years

open access: yesScientific Reports, 2021
Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) has emerged as an important cause of infection. We conducted a longitudinal study to evaluate changes in clinical and microbiological characteristics as well as outcomes of sequence ...
Eunmi Yang   +11 more
doaj   +1 more source

Living Microbial Drugs

open access: yesChemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik   +3 more
wiley   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma   +6 more
wiley   +1 more source

Clinical Evaluation of the Effectiveness of Digital Peroral Cholangioscopy‐Guided Lithotripsy for Difficult Bile Duct Stones

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background and Aims Peroral cholangioscopy‐guided lithotripsy (POCS‐L) has emerged as a treatment option for difficult bile duct stones (DBDSs), but detailed evidence remains limited. This study evaluated its effectiveness, safety, and risk factors for adverse events (AEs).
Hirohito Minami   +9 more
wiley   +1 more source

Persistence of positive Brucella Melitensis blood cultures is not associated with focal infection

open access: yesInternational Journal of Infectious Diseases
Objectives: Brucellosis is a global zoonotic disease complicated by focal infections requiring treatment modifications. In other bacterial infections, persistent positive blood cultures prompt evaluation for metastatic foci.
Meir Cherniak   +3 more
doaj   +1 more source

Renal screening sonography—A comparative study in a Portuguese basic emergency service

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 8-16, March 2025.
Renal sonography screening aids in clinical decision‐making for patients with suspected renal colic. This study intends to compare the accuracy and pertinence of sonographic findings obtained by a sonographer in a Basic Emergency Service (BES) with that of radiologists at Referral Hospital (RH) in Portugal. Renal sonography screening was able to detect
Sérgio Miravent   +9 more
wiley   +1 more source

Impact of the Novel Prophage ϕSA169 on Persistent Methicillin-Resistant Staphylococcus aureus Endovascular Infection

open access: yesmSystems, 2020
Persistent methicillin-resistant Staphylococcus aureus (MRSA) endovascular infections are life-threatening syndromes with few therapeutic options. The potential impact of bacteriophages on the persistent outcome has not been well studied.
Liang Li   +8 more
doaj   +3 more sources

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