Results 171 to 180 of about 54,259 (246)

Identifying Transient Cells During Reprogramming via Persistent Homology. [PDF]

Annu Int Conf IEEE Eng Med Biol Soc, 2022
Petenkaya A, Manuchehrfar F, Chronis C, Liang J.   +3 more
europepmc   +1 more source

AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling

Advanced Science, EarlyView.
This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi, Minying Low, Peng Xiu, Kresten Lindorff‐Larsen, Yong Wang   +4 more
wiley   +1 more source

Colony Binary Classification Based on Persistent Homology Feature Extraction and Improved EfficientNet. [PDF]

Bioengineering (Basel)
Wang Z, Yang K, Tang J, Gao J, Zhang Y, Xu W, Huang CM.   +6 more
europepmc   +1 more source

The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton

Advanced Science, EarlyView.
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang, Jie Dai, Ting Zhao, Shengjun Zhao, Hongyu Wu, Jiaying Pan, Yupeng Hao, Ke Nie, Li Yu, Yumeng Zhu, Xiangyi Zhao, Kai Huang, Mengke Zhang, Yongyan Zhao, Yaping Jiang, Siyuan Wang, Yiling Pan, Yubing Chen, Yilai Lin, Wanghong Shi, Yayuan Deng, Jin Han, Jie Li, Xuan Long, Junbin Wang, Zhiyuan Zhang, Zegang Han, Zhanfeng Si, Lei Ju, Jun Li, Tianzhen Zhang, Ji Zhou, Xueying Guan   +32 more
wiley   +1 more source

Identifying key genes in cancer networks using persistent homology. [PDF]

Sci Rep
Ramos RH, Bardelotte YA, de Oliveira Lage Ferreira C, Simao A.   +3 more
europepmc   +1 more source

A Spatiotemporal Brain Network Analysis of Alzheimer's Disease Based on Persistent Homology. [PDF]

Front Aging Neurosci, 2022
Xing J, Jia J, Wu X, Kuang L.
europepmc   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

Method for persistent topological features extraction of schizophrenia patients' electroencephalography signal based on persistent homology. [PDF]

Front Comput Neurosci, 2022
Guo G, Zhao Y, Liu C, Fu Y, Xi X, Jin L, Shi D, Wang L, Duan Y, Huang J, Tan S, Yin G.   +11 more
europepmc   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Filipino sign language alphabet recognition using Persistent Homology Classification algorithm. [PDF]

PeerJ Comput Sci
Jetomo CB, De Lara MLD.
europepmc   +1 more source