Results 121 to 130 of about 51,545 (286)
This presentation discusses the different perspectives of researchers within the humanities and from a computer scientist and web archivist. The presentation will cover challenges and experiences from each perspective as well as future potentials in ...
Nyvang, Caroline, Zierau, Eld
core
13e Algemene volkstelling 31 mei 1960
, 2009 The dataset is based on the population census of the Netherlands of 1960 published in 14 vols. Content: images of the publication. See also the 'Census data 1960' in this archive (Persistent identifier: urn:nbn:nl:ui:13-4zc ...
NIWI - KNAW +1 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Recording of a presentation that discusses the different perspectives of researchers within the humanities and from a computer scientist and web archivist.
Nyvang, Caroline, Zierau, Eld
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Structured Metadata for Direct Resource Location: A Case Study [PDF]
, 2003 This paper proposes that for scientific and technical information resources, a well-structured and high-quality metadata record contains enough information to find that resource on the Internet, and as a consequence, no additional human labour is needed ...
Katz, Stephen +5 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
THE ROLE OF PERSISTENT IDENTIFIERS IN E-SCIENCE
Journal of Social Sciences, 2019 The transformations in science produced by the development of ICTs are conceptualized in the model of e-Science. Information on the researchers’ activities in digital form is collected in several systems outside the affiliated institutions. Manuscript submission systems, grant funding applications, data centers, citation indexes, other institutional or
openaire +3 more sources