Results 121 to 130 of about 772,455 (279)

Open Citation Identifier: Definition

open access: yes, 2019
This document describes the Open Citation Identifier (OCI), a globally unique persistent identifier (PID) for the identification of open bibliographic citations stored in a specific database or in other kinds of storages.
David Shotton (100109)   +1 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Persistent Identifier ecosystem expands – to instruments!

open access: yes, 2020
A PID or persistent identifier has been in common use in scientific publishing for around 20 years now. It was introduced as a DOI (Digital Object Identifier), and the digital object in this case was the journal article.
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Persistent identifier distributed system for digital libraries

open access: yes, 2010
In this paper we present an Italian initiative, involving relevant research institutions and national libraries, aimed at implementing an NBN Persistent Identifiers (PI) infrastructure based on a novel hardware/software architecture.
Brunella Sebastiani   +7 more
core   +1 more source

Linking Persistent Identifiers At The British Library

open access: yes, 2017
Presentation given at the Crossref-THOR outreach meeting: Much more than infrastructure: working together to connect research.
openaire   +2 more sources

A Persistent Identifier e-Infrastructure: Paper - iPRES 2014 - Melbourne

open access: yes, 2015
Persistent identifiers (PIDs) have been recognized as a crucial enabling component for 2020 e-science infrastructures, having the potential of providing global keys for information access, reuse and exchange and creating a complex network of links which ...
Bazzanella, Barbara
core  

LAPIS API for Persistent Identifier Services v0.2.2

open access: yes, 2016
<p>LAPIS API for Persistent Identifier Services v0.2.2</p> <p>LAPIS is a Python project that aims to enhance the use of Persistent Identifiers for applications within data infrastructures or software tools with a focus on building ...
Tobias Weigel, Tobias Weigel (5303977)
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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