Results 101 to 110 of about 819,498 (286)
, 2020 https://www.rd-alliance.org/persistent-identifier-policy-rules-participation-metrics-and-service-certification-eosc-documents ...
Klaus Graf
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Implementing Persistent Identifiers
, 2019 Traditionally, organisations have relied on URL hyperlinks to provide interested parties with access to their digitised content via the internet. However, over time, more and more of these hyperlinks are ‘broken’. The URL relies on providing the specific location details for a document.
Hilse, Hans-Werner, Kothe, Jochen
openaire +2 more sources
13e Algemene volkstelling 31 mei 1960
, 1998 The dataset is based on the population census of the Netherlands of 1960 published in 14 vols. Content: images of the publication. See also the 'Census data 1960' in this archive (Persistent identifier: urn:nbn:nl:ui:13-4zc ...
NIWI - KNAW +1 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Wikidata and Persistent Identifiers
, 2016 Presentation on the wikidata service and its relationship to existing and potential future persistent identifiers of relevance to scholarly communications.
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A Persistent Identifier Strategy for NWO
, 2022 22 slides.-- Presentation delivered within Session 2 "Recent research information developments in the Netherlands (II)"The presentation introduces the NWO Persistent Identifier Strategy issued in Apr 2021 by the Dutch Research Council (NWO).
Cruz, Maria
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source