Results 91 to 100 of about 819,498 (286)
Persistent Identifiers and URLs [PDF]
, 2015 Just like the rest of the internet, much of our scholarly infrastructure is built around the Hypertext Transfer Protocol (HTTP), increasingly HTTPS for security, and soon HTTP/2 for better performance. In this infrastructure Universal Resource Locators (URLs) are essential to locate resources (sic) such as scholarly articles, datasets, researchers ...
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 2020 This policy states the ARDC’s rationale, intent and broad course of action regarding persistent identifiers (PIDs).
openaire +1 more source
ORCID in the Open Science scenario: opportunities for academic libraries
Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2019 The persistent identification of authors and contributors plays a decisive role within the Open Science landscape. The increasing number of published research products and new open publishing models and infrastructures requires author identification ...
Paloma Marín-Arraiza
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
University Library at a New Stage of Social Communications DevelopmentObjective. The article is devoted to the study of the role of academic libraries in the advancing of the ecosystem of open science by foreign and domestic authors of the university community. Methods. The following general scientific methods were used in
M. M. KULYK
doaj +1 more source
Persistent Identifier für wissenschaftliche Einrichtungen
, 2018 In der vorliegenden Arbeit werden Probleme bei der eindeutigen Identifizierung wissenschaftlicher Einrichtungen aufgezeigt, Persistent Identifier als Lösung dieser Probleme vorgeschlagen und bereits bestehende Lösungsansätze in Form von ...
Rothfritz, Laura; https://orcid.org/0000-0001-7525-0635; https://d-nb.info/gnd/1202262562
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