Results 71 to 80 of about 51,545 (286)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Persistent hyper-programs

open access: yes, 2011
This work was supported by ESPRIT III Basic Research Action 6309 – FIDE 2 and SERC grant GR/F 02953.The traditional representation of a program as a linear sequence of text forces a particular style of program construction to ensure good programming ...
Dearle, Alan   +5 more
core  

PersID - I: Project report

open access: yes, 2011
This report is one of five reports with the outcomes of the PersID project commissioned by Knowledge Exchange and SURFfoundation.
Bas Cordewener, SURFfoundation (author/editor)
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Power and Persistent Identifiers

open access: yes, 2018
Persistent identifiers are critical components of modern and evolving data infrastructure. Like much of the mechanics of civilization, PIDs are based on trusted registries. The operation of these registries can have significant power over how and when data are shared.
Parsons, Fox
openaire   +3 more sources

Persistent Identifier in Open-Access-Publikationsworkflows

open access: yes, 2022
In einer mittlerweile überwiegend digitalen Wissenschaftslandschaft ist die dauerhafte und verlässliche Identifizierung der mit Forschungsprozessen verknüpften Ressourcen, seiner Akteure und ihrer Publikationen mittels Persistent Identifiern (PIDs ...
Schirrwagen, Jochen ; https://orcid.org/   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The National Bibliography Number Italia (NBN:IT) Project. A persistent identifier supporting national legal deposit for digital resources

open access: yesJLIS.it, 2012
The association of a persistent identifier to a digital resource is a best practice helping in solving a reliable information resources retrieving on the web, other than the Internet Error 404.
Emanuele Bellini   +12 more
doaj   +6 more sources

Normdatenverknüpfungen aus Culturegraph für die Bildungsforschung (und darüber hinaus)

open access: yeso-bib. Das offene Bibliotheksjournal
Der Fachinformationsdienst (FID) Erziehungswissenschaft und Bildungsforschung hat die Zielsetzung, seine Literaturnachweise im Fachportal Pädagogik systematisch mit Normdaten zu verknüpfen. Ein höheres Maß an Normierung bietet im Bereich der Autorschaft
Marcel Jungmann   +2 more
doaj   +1 more source

Diagnosis of neglected tropical diseases among patients with persistent digestive disorders (diarrhoea and/or abdominal pain ≥14 days) : Pierrea multi-country, prospective, non-experimental case-control study [PDF]

open access: yes, 2015
Diarrhoea still accounts for considerable mortality and morbidity worldwide. The highest burden is concentrated in tropical areas where populations lack access to clean water, adequate sanitation and hygiene.
Bratschi, Martin W   +58 more
core   +1 more source

Home - About - Disclaimer - Privacy