Results 111 to 120 of about 2,614,626 (301)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

In-Vivo Expression Profiling of Pseudomonas aeruginosa Infections Reveals Niche-Specific and Strain-Independent Transcriptional Programs [PDF]

, 2011
Pseudomonas aeruginosa is a threatening, opportunistic pathogen causing disease in immunocompromised individuals. The hallmark of P. aeruginosa virulence is its multi-factorial and combinatorial nature.
Justyna Glik, Nowak Mariusz, Weiss, Siegfried, Wos-Oxley, Melissa L, Wos-Oxley Melissa L., Kawecki Marek, Melissa L Wos-Oxley, Nowak, Mariusz, dos Santos, Vítor A P Martins, Jacek Puchałka, Puchalka, J., Melissa L. Wos-Oxley, Glik, Justyna, Bielecki, P., Siegfried Weiss, Piotr Bielecki, Burkhard Tümmler, Vítor A. P. Martins dos Santos, Mariusz Nowak, Vítor A P Martins dos Santos, Tümmler Burkhard, Weiss Siegfried, Holger Loessner, Loessner, Holger, Loessner Holger, Wos-Oxley, M.L., dos Santos Vítor A. P. Martins, Martins Dos Santos, V.A.P., Tümmler, Burkhard, Kawecki, Marek, Bielecki Piotr, Glik Justyna, Puchałka Jacek, Puchałka, Jacek, Marek Kawecki, Bielecki, Piotr   +35 more
core   +2 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Persistent Bovine Viral Diarrhea Virus infection in domestic and wild small ruminants and camelids including the mountain goat (Oreamnos americanus)

Frontiers in Microbiology, 2016
Bovine viral diarrhea virus (BVDV) is a Pestivirus best known for causing a variety of disease syndromes in cattle, including gastrointestinal disease, reproductive insufficiency, immunosuppression, mucosal disease, and hemorrhagic syndrome.
Danielle Darracq Nelson, Jennifer L Duprau, Peregrine Lee Wolff, James Frederick Evermann   +3 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Penicillin kills chlamydia following the fusion of bacteria with Lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice [PDF]

, 2013
The obligate intracellular bacterium Chlamydia exists as two distinct forms. Elementary bodies (EBs) are infectious and extra-cellular, whereas reticulate bodies (RBs) replicate within a specialized intracellular compartment termed an ‘inclusion ...
Le Gall, SM, Colette Kanellopoulos-Langevin, Le Gall Sylvain M., Habbeddine, M, Sylvain M. Le Gall (108751), Habbeddine, Mohamed, Delarbre, C., Dumoux, M, Maud Dumoux (501153), Dumoux, Maud, Delarbre, C, Dumoux Maud, Christiane Delarbre, Hayward Richard D., Philippe Verbeke, Delarbre Christiane, Verbeke, Philippe, Kanellopoulos-Langevin Colette, Kanellopoulos-Langevin, C, Le Gall, Sylvain M, Habbeddine Mohamed, Philippe Verbeke (16975), Hayward, RD, Hayward, Richard D, Richard D Hayward, Christiane Delarbre (501155), Delarbre, Christiane, Le Gall, S.M., Habbeddine, M., Kanellopoulos-Langevin, C., Hayward, Richard D., Colette Kanellopoulos-Langevin (146985), Mohamed Habbeddine (501154), Ramsey, K., Richard D. Hayward (272234), Verbeke, P., Verbeke, P, Kanellopoulos-Langevin, Colette, Sylvain M Le Gall, Maud Dumoux, Mohamed Habbeddine, Verbeke Philippe   +41 more
core   +2 more sources

Phenotypic modifications in Staphylococcus aureus cells exposed to high concentrations of vancomycin and teicoplanin

Frontiers in Microbiology, 2016
Bacterial cells are known to change the fatty acid composition of the phospholipids as a phenotypic response to environmental conditions and to the presence of toxic compounds such as antibiotics.
Fábio D.A. Gonçalves, Carla C. C. R. de Carvalho   +1 more
doaj   +1 more source

Editorial: The interaction between viruses and the host immune system in persistent infection from a metabolic perspective

Frontiers in Cellular and Infection Microbiology, 2023
Wei Xiong, Yong Feng, Yang Qiu, Yuncong Yuan, Chao Shen   +4 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Analysis of risk factors for persistent infection of asymptomatic women with high-risk human papilloma virus

Human Vaccines & Immunotherapeutics, 2017
Objective: This study aims to prevent persistentinfection, reduce the incidence of cervical cancer, and improve women's health by understanding the theoretical basis of the risk factors for continuous infection of asymptomatic women with high-risk human ...
Nianmin Shi, Qiang Lu, Jiao Zhang, Li Li, Junnan Zhang, Fanglei Zhang, Yanhong Dong, Xinyue Zhang, Zheng Zhang, Wenhui Gao   +9 more
doaj   +1 more source