Results 161 to 170 of about 2,614,626 (301)

NFX1-123 is required for keratinocyte differentiation and HPV 16 DNA maintenance in early and persistent infection models. [PDF]

J Virol
Dankoski MA, Thompson D, Quist KM, Katzenellenbogen RA.   +3 more
europepmc   +1 more source

Mycobacterium tuberculosis IDH-PPARγ interaction suppresses GPX4 to drive macrophage ferroptosis and sustain persistent infection. [PDF]

Nat Commun
Pu W, Zhang X, Tian M, He Z, Zhu J, Song S, Li L, Lian P, Lu R, Wang R, Lin K, Gu C, Wazir J, Wang C, Sun Y, Yang J, Zhang Y, Chen H, Petretto E, Cao W, Fan R, Treuter E, Zhang X, Liu N, Yang A, Chen X, Wang H, Huang Z.   +27 more
europepmc   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Correction: Shedding dynamics of a DNA virus population during acute and long-term persistent infection. [PDF]

PLoS Pathog
Blois S, Goetz BM, Mojumder A, Sullivan CS.   +3 more
europepmc   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Molecular Network Analysis of HBV Persistent Infection from the Perspective of Whole Transcriptome. [PDF]

Biomolecules
Chen Q, Tang C, Hu H, Peng Y, Liu J, Wu P, Feng Q, Jiang Y, Li B.   +8 more
europepmc   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Third-generation cephalosporin-induced L-form transition in <i>Shigella sonnei</i> reveals a virulence-survival trade-off underlying persistent infection. [PDF]

Microbiol Spectr
Das S, Mukherjee A, Halder P, Banerjee S, Mandal S, Roy N, Debnath A, Banerjee S, Manna M, Mandal U, Mitobe J, Withey JH, Mukhopadhyay AK, Das S, Howlader DR, Koley H.   +15 more
europepmc   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Flaviviridae RdRp exploits NSUN2-driven m5C methylation to establish persistent infection. [PDF]

PLoS Pathog
Chen J, Zhong LH, Chen JX, Song HX, Zou LK, Bi XQ, Zhao BQ, Li MZ, Li K, Wang K, Yang JJ, Cui J, Wang L, Zhou B.   +13 more
europepmc   +1 more source