Results 41 to 50 of about 2,065,251 (228)

Evidence‐Informed Multidisciplinary Consensus Guidance for the Psychosocial Care of Adolescents With High‐Risk Cancer: Recommendations From the Italian Association of Pediatric Hematology and Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom, Dorella Scarponi, Giulia Zucchetti, Teresa Perillo, Maria Montanaro, Elisa Marconi, Chiara Rutigliano, Paolo Colavero, Paola Quarello, Marina Bertolotti, Monica Cellini, Carlo Clerici, Maurizio Mascarin, Francesca Bomben, Andrea Ferrari, the expert workgroup   +15 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Modelling the dynamics of intramammary E. coli infections in dairy cows: understanding mechanisms that distinguish transient from persistent infections [PDF]

, 2009
The majority of intramammary infections with Escherichia coli in dairy cows result in transient infections with duration of about 10 days or less, although more persistent infections (2 months or longer) have been identified.
Green, L, Döpfer, D, Medley, GF, Laura Green, Graham F. Medley, Medley, Graham F., Belgin Dogan, Lisa J. White, White, Lisa, Chappell, M. J. (Michael J.), Dogan, B, Green, Laura, Chappell, Mike J., Ynte H. Schukken, White, Lisa J., Schukken, Ynte H., Chappell, MJ, Dogan, Belgin, Schukken, Y. H., Schukken, YH, White, L. J., Mike J. Chappell, Dörte Döpfer, Medley, Graham, Green, Laura E., White, LJ, Green, Laura; id_orcid, Döpfer, Dörte   +27 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Somatic symptoms and psychological concerns in a general adolescent population: Exploring the relevance of DSM-5 Somatic Symptom Disorder [PDF]

, 2015
OBJECTIVE: DSM-5 somatic symptom disorder (SSD) constitutes a major change for psychosomatic medicine and psychiatry, as well as for epidemiological research in these fields.
Rydelius, Per-Anders,, van Geelen, SM, Hagquist, Curt, Hagquist, Curt,, Van Geelen, Stefan,, Rydelius, Per-Anders   +5 more
core   +2 more sources

Empirical assessment of functional somatic disorder (FSD): frequency, applicability, and diagnostic refinement in a population-based sample

BMC Medicine
Background Persistent and troublesome physical symptoms are common and can, regardless of their cause, greatly impair patients’ quality of life. Reflecting complex brain-body interactions, they are observed across all healthcare specialties, commonly ...
Abigail Smakowski, Judith Rosmalen, Bernd Löwe, Christopher Burton, Anne Toussaint   +4 more
doaj   +1 more source

Novel intervention of high-frequency repetitive transcranial magnetic stimulation in patients with somatic symptom disorder and its safety and outcome

Indian Journal of Psychiatry, 2023
Somatic Symptom disorders (SSDs) are characterised by the presence of persistent somatic symptoms associated with excessive thoughts, feelings and behaviours related to the symptoms.
Nand Kumar, Prakamya Singal, Abhishek Chakladar   +2 more
doaj   +1 more source

Quality indicators for collaborative care networks in functional disorders and persistent somatic symptoms: a Delphi study

, 2022
Utilising a modified Delphi process, health and social care professionals with experience of providing care for people with functional disorders and persistent somatic symptoms in the context of a collaborative care network will be asked for possible ...
Manouk van de Klundert, Bernd Löwe, Tim olde Hartman, ETUDE, Anne Toussaint, Denise Hanssen, Lineke Tak, Kerstin Maehder, Judith Rosmalen, Nick Mamo   +9 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source