Results 51 to 60 of about 2,065,251 (228)

Clinical utility of the Functional Somatic Disorder (FSD) diagnostic proposal for persistent somatic symptoms in a psychosomatic outpatient department

, 2023
This study will assess the clinical utility of the new diagnostic proposal for Functional Somatic Disorder in a secondary care setting for patients with persistent somatic symptoms in the context of Somatic Symptom Disorder and Somatoform Disorders.
Bernd Löwe, Anne Toussaint, Abigail Smakowski   +2 more
core   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Efficacy of a mechanism-based psychological intervention for persistent gastrointestinal symptoms in ulcerative colitis and irritable bowel syndrome: results of a three-arm randomised controlled trial (SOMA.GUT-RCT)Research in context

EClinicalMedicine
Summary: Background: Irritable Bowel Syndrome (IBS) and Ulcerative Colitis (UC) are chronic gastrointestinal conditions with differing pathologies but overlapping symptoms and shared risk factors contributing to symptom persistence.
Kerstin Maehder, Luisa Peters, Sina Hübener, Anna Matysiak, Samuel Huber, Anne Toussaint, Antonia Zapf, Eik Vettorazzi, Philipp Weber, Katharina Stahlmann, Viola Andresen, Yvonne Nestoriuc, Ansgar W. Lohse, Bernd Löwe   +13 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Association of Central Sensitisation with Depression, Anxiety, and Somatic Symptoms: A Cross-Sectional Study of a Mental Health Outpatient Clinic in Japan

Life
For patients with chronic pain and persistent physical symptoms, understanding the mechanism of central sensitisation may help in understanding how symptoms persist.
Takeaki Takeuchi, Kazuaki Hashimoto, Akiko Koyama, Keiko Asakura, Masahiro Hashizume   +4 more
doaj   +1 more source

Functional somatic symptoms [PDF]

, 2023
Every individual experiences subjective somatic symptoms that might or might not be explained by a known medical condition. Some of these symptoms disappear quickly, whereas others persist.
Henningsen, Peter, Hausteiner-Wiehle, Constanze, Bouman, Theo K, Bouman, Theo K; id_orcid   +3 more
core   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

The course and management of symptom diagnoses in general practice

Scandinavian Journal of Primary Health Care
Background In general practice, symptom diagnoses are commonly used when patients seek care for symptoms in which no specific disease or disorder can be diagnosed.
Asma Chaabouni, Suraya Jubar, Juul Houwen, Reinier Akkermans, Iris Walraven, Kees van Boven, Tim olde Hartman, Henk Schers   +7 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Findings Consistent with a Breast Implant–associated Somatic System Disorder (BIA-SSD) Among Patients Self-reporting Breast Implant Illness

Plastic and Reconstructive Surgery, Global Open
Background:. Self-reported breast implant illness (BII) has been found to be associated with anxiety as well as medically diagnosed anxiety and depression.
Stephen D. Bresnick, MD, Susie Morris, MD, Carlito Lagman, MD   +2 more
doaj   +1 more source