Results 51 to 60 of about 2,464,313 (253)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Preventing adolescents’ externalizing and internalizing symptoms : effects of the Penn Resiliency Program [PDF]

, 2013
This study reports secondary outcome analyses from a past study of the Penn Resiliency Program (PRP), a cognitive-behavioral depression prevention program for middle-school aged children.
Rachel M. Abenavoli, Abenavoli, Rachel M., Derek R. Freres, Gillham, Jane E., Karen J. Reivich, Robert J. Gallop, J. J. Cutuli, Chaplin, Tara M., Cutuli, J.J., Reivich, Karen J., Jane E. Gillham, Tara M. Chaplin, Martin E. P. Seligman, Seligman, Martin E.P., Gallop, Robert J., Freres, Derek R.   +15 more
core   +1 more source

Burden of illness of people with persistent symptoms of schizophrenia: A multinational cross-sectional study.

, 2017
BACKGROUND Few studies have examined the impact of persistent symptoms of schizophrenia, especially with respect to patient-reported outcomes (PROs), carer burden and health economic impact.
Bernasconi, Corrado Angelo, Nordstroem, Anna-Lena, Talbot, Darren, Lalonde, Justine, Berardo, Carmen Galani   +4 more
core   +1 more source

The effects of persistent mild traumatic brain injury symptoms on the neurophysiological health of adults

, 2021
Buckley, Thomas A.BACKGROUND: Mild traumatic brain injury (mTBI) accounts for approximately 70-90% of the 2.8 million TBIs sustained annually, and up to 40% of those may result in persistent symptoms lasting beyond a normal clinical recovery timeline ...
Bryk, Kelsey N.
core   +1 more source

Prevalence of persistent physical symptoms and association with depression, anxiety and health anxiety in Iceland [PDF]

, 2021
INTRODUCTION: Persistent physical symptoms that are medically unexplained can result in significant functional impairment. The aim of this study was to estimate the prevalence of persistent physical symptoms among people seeking primary healthcare in ...
Brynjolfsson, Sturla, Sigurdsson, Jon Fridrik, Flovenz, Sigrun Olafsdottir, Broddadottir, Elin, Salkovskis, Paul M, Agnarsdottir, Agnes Sigridur   +5 more
core   +1 more source

Reflection and hyper-programming in persistent programming systems [PDF]

, 2011
In an orthogonally persistent programming system, data is treated in a manner independent of its persistence. This gives simpler semantics, allows the programmer to ignore details of long-term data storage and enables type checking protection ...
Kirby, Graham N. C.
core   +2 more sources

Empirical assessment of functional somatic disorder (FSD): frequency, applicability, and diagnostic refinement in a population-based sample

BMC Medicine
Background Persistent and troublesome physical symptoms are common and can, regardless of their cause, greatly impair patients’ quality of life. Reflecting complex brain-body interactions, they are observed across all healthcare specialties, commonly ...
Abigail Smakowski, Judith Rosmalen, Bernd Löwe, Christopher Burton, Anne Toussaint   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Persistent negative symptoms in schizophrenia: an overview [PDF]

, 2007
Persistent negative symptoms represent an alternative ap-proach for assessing negative symptoms in the context of clinical trials. Persistent negative symptoms are designed to capture those symptoms that lead to functional impair-ment but are currently ...
Robert W. Buchanan, Robert W Buchanan
core  

Persistent fluctuations in stride intervals under fractal auditory stimulation [PDF]

, 2014
Copyright @ 2014 Marmelat et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and ...
Beek, P.J., Beek, PJ, Andreas Daffertshofer, Kjerstin Torre (355432), Beek Peter J., Daffertshofer, A.; id_orcid, Vivien Marmelat (540065), Daffertshofer, Andreas, Torre Kjerstin, Kjerstin Torre, Marmelat, V, Torre, K, Marmelat Vivien, Marmelat, Vivien, Daffertshofer, A, Beek, P.J.; id_orcid, Torre, K., Peter J Beek, Daffertshofer Andreas, Vivien Marmelat, Beek, Peter J., Peter J. Beek (307441), Torre, Kjerstin, Marmelat, V.C.M., Andreas Daffertshofer (238842), Daffertshofer, A.   +25 more
core   +3 more sources