Results 61 to 70 of about 2,828,467 (301)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Filatelisty w getcie warszawskim przypadki. Historia Franza Konrada

Zagłada Żydów, 2011
Franz Konrad, the head of the Werterfassung – and institution which seized and secured the property the deported Jews left behind in the Warsaw ghetto – was one of the key figures in the ghetto after the Great Deportation Action.
Katarzyna Person
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Une étrange apparition. L'ambiguïté du Schein dans la Science de la Logique de Hegel

Mosaïque, 2013
Cet article mène une étude suivie du concept d’Apparence (Schein) dans la Logique de l’essence afin d’en dévoiler l’ambiguïté foncière. L’enjeu est de ressaisir cette ambiguïté comme étant celle-là même du Concept.
Quentin Person
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A systematic review employing a best-evidence synthesis approach of mechanistic pathways linking physical activity and cognitive function in older adults

Discover Public Health
Background Physical activity (PA) is associated with improved cognitive outcomes in older adults, yet the biological and psychosocial mechanisms through which PA exerts these benefits remain inadequately understood.
Konstantinos Baliotis, Zoe Konstanti, Nektaria Zagorianakou, Aneta Toti, Elena Dragioti, Fotios Tatsis, Stefanos Mantzoukas, Mary Gouva, Michael Kourakos   +8 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Neoliberalismo en la Universidad Metropolitana de Manchester... y una alternativa

Revista Teknokultura, 2012
Una campaña contra la persecución a miembros del sindicato de la Metropolitan University of Manchester (MMU) ha logrado una victoria importante. La campaña ha sido liderada por el University and College Union (UCU) y un grupo de estudiantes de postgrado ...
Third Person
doaj   +1 more source