Results 71 to 80 of about 2,357,083 (312)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Copy of letter: H.S. Person to Mr. Thompson, September 2, 1922

open access: yes, 1922
Copy of letter for Miss Tarbell, 3 ...
Person, H.S.
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Validity and test-retest reliability of the self-completion adult social care outcomes toolkit (ASCOT-SCT4) with adults with long-term physical, sensory and mental health conditions in England

open access: yesHealth and Quality of Life Outcomes, 2017
Background The Adult Social Care Outcomes Toolkit (ASCOT-SCT4) is a multi-attribute utility index designed for the evaluation of long-term social care services. The measure comprises eight attributes that capture aspects of social care-related quality of
Stacey Rand   +4 more
doaj   +1 more source

Yves Person

open access: yes, 1977
Person Yves. Yves Person. In: Autogestion et socialisme : études, débats, documents, N°37-38, 1977. 1966-1976. Traces, contradictions, projets - Bakounine et l’autogestion - Conseils ouvriers et autogestion en Europe de l’Est. pp.
Person, Yves
core  

Person-centred counsellors’ experiences of working within time boundaries: A heuristic informed enquiry [PDF]

open access: yes, 2011
Many counselling services are finding it necessary, due to limited resources, to limit the total number of sessions available to each service user, whilst also providing quality evidence-based practice.
Hynes, Liz
core  

The Demonstrative Model of first-person thought [PDF]

open access: yes, 2014
What determines the reference of first-person thoughts—thoughts that one would express using the first-person pronoun? I defend a model on which our ways of gaining knowledge of ourselves do, in much the way that our ways of gaining knowledge of objects ...
Morgan, D, Morgan, Daniel, Daniel Morgan
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Reconnaissance et dessaisissement de soi dans la Première Philosophie de l’Esprit de Hegel

open access: yesMosaïque, 2011
Lorsqu’il formule dans son Système de la vie éthique le motif d’une « lutte à mort » pour la reconnaissance éthique des individus Hegel n’entend pas promouvoir les particularités individuelles sur la scène universelle.
Quentin Person
doaj   +1 more source

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