Results 141 to 150 of about 2,995,343 (301)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
LearnPCC scientific conference held in Gothenburg, Sweden, on 12–13 December 2024The inaugural LearnPCC scientific conference was held in Gothenburg, Sweden, on 12–13 December 2024. Organised by the Centre for Person-Centred Care (GPCC) at the University
LearnPCC Conference 1 2024 Göteborg
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Dual‐granularity feature fusion in visible‐infrared person re‐identification
IET Image ProcessingVisible‐infrared person re‐identification (VI‐ReID) aims to recognize images of the same person captured in different modalities. Existing methods mainly focus on learning single‐granularity representations, which have limited discriminability and weak ...
Shuang Cai, Shanmin Yang, Jing Hu, Xi Wu
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Gericht Katzenberg in Hessen / durch N. Person
Appartient à l’ensemble documentaire ...
Person, Nicolaus (166.-1710). Cartographe
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Death certificate: Bishop Person
, 1917 This is a photograph of the death certificate for Bishop Person, deceased on 1917-06-22, filed with the Arkansas Department of Health by the Ruebel Funeral Home in Little Rock.Transcribed.
Ruebel Funeral Home (Little Rock, Ark.)
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Determining a language’s feature inventory: person in Archi [PDF]
, 2017 In descriptions of languages, we make use of morphosyntactic features such as gender, number or person. This paper shows that sometimes choosing the features and values to describe a language is not straightforward, and the decision of whether or not to ...
Kibort, A, Chumakina, M, Corbett, GG
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source