Results 121 to 130 of about 2,278,305 (352)
Perfil Criminal de una Persona Psicópata: El Caso de Ted Bundy
, 2023 Marina I. Méndez V. +4 more
openalex +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
La nacionalidad de las personas nacidas en el antiguo Sahara español [PDF]
, 2021 Celia Martínez Escribano
openalex +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Pronomina Persona Bahasa Melayu Riau Subdialek Baserah Kecamatan Kuantan Hilir Kabupaten Kuantan Singingi [PDF]
, 2015 Persona is the word personal pronouns a substitute who used to replace a word refers to persons.Persona of pronouns is also used by the community of Baserah in sub district of Kuantan Hilir, Kuantan SingingiRegency.
AR, H. F. (Hasnah) +2 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
PERSONA, TECNICA E NEUROSCIENZE [PDF]
, 2019 Il percorso qui proposto si avvale di una prospet- tiva antropologico-filosofica e di una etica di carattere personalistico, che indicano nell’inter- connessione dei saperi la base per la costruzione di un ponte fra neuroscienze e scienze umane.
Zingarelli, A.
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Persona y medio ambiente [PDF]
, 2010 10 p.Los primeros filósofos de los que tenemos noticia, conocidos como presocráticos o filósofos de la naturaleza, lo son, precisamente, por su interés en indagar. Ahora bien, ¿por qué es como es y no de otra manera?
Rubiano-Segura, Leonor
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