Results 151 to 160 of about 2,337,590 (401)

En primera persona [PDF]

open access: yes, 2017
El artista debe tener un pensamiento autónomo, y conectar con su “Yo” de forma más directa que el resto de la sociedad. Sin duda es el proceso de creación lo que te conecta con tu interior más profundo.
Gómez Álvarez, María del Valle
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Dialogue Language Model with Large-Scale Persona Data Engineering [PDF]

open access: yesarXiv
Maintaining persona consistency is paramount in the application of open-domain dialogue systems, as exemplified by models like ChatGPT. Despite significant advancements, the limited scale and diversity of current persona dialogue datasets remain challenges to achieving robust persona-consistent dialogue models.
arxiv  

Getting personal: exploring the usage of persona in order to optimize the involvement of a living lab panel [PDF]

open access: yes, 2015
iMinds Living Labs started with living lab research in 2009. Living lab research involves gathering user feedback on innovations implemented in a real-life context (Eriksson et al., 2005).
Logghe, Sara
core   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

DEEPER Insight into Your User: Directed Persona Refinement for Dynamic Persona Modeling [PDF]

open access: yesarXiv
To advance personalized applications such as recommendation systems and user behavior prediction, recent research increasingly adopts large language models (LLMs) for human -readable persona modeling. In dynamic real -world scenarios, effective persona modeling necessitates leveraging streaming behavior data to continually optimize user personas ...
arxiv  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

The Singer of Tibet: Shabkar (1781-1851), the “Inescapable Nation,” and Buddhist Universalism [PDF]

open access: yes, 2018
This paper examines the concept of ‘Tibet (Tib. bod)’ in the spiritual autobiography of the celebrated Tibetan Buddhist author, Shabkar Tsokdruk Rangdröl (1781–1851).
Pang, Rachel H
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Research of some psychical qualities of cadets' personality with the aid of psychogeometric test [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
The results of application of psychogeometric test are given. A test is used studies of some properties of personality of students of military institute. 298 students of different soldiery specialities took part in researches.
Afonin V.M., Kuprinenko O.V.
doaj  

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