Results 211 to 220 of about 2,278,305 (352)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Expansion of Personas to Guide Professional Development in Implementing Evidence-Based Practices in Diverse Institutions. [PDF]
CBE Life Sci EducDunbar-Wallis AK +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Aligning large language models for cognitive behavioral therapy: a proof-of-concept study. [PDF]
Front PsychiatryKim Y, Choi CH, Cho S, Sohn JY, Kim BH.
europepmc +1 more source
Razones por las cuales las personas entre 18-20 años asiste al gimnasio Forza Gym en Chetumal
Maria Ángeles
openalex +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Using personas and journey maps as knowledge translation tools to enhance clinicians' interpretation of PROM scores. [PDF]
J Patient Rep OutcomesKwon JY +4 more
europepmc +1 more source