Results 61 to 70 of about 214,122 (263)

LA PROBLEMATICA DEL DAÑO A LA PERSONA

open access: yes, 2018
Un'indagine sulle attuali problematiche dei danni alla persona nelle principali esperienze di Civil Law, con particolare riguardo alle diverse tipologie di danno (danno alla salute, danno da perdita della vita, danno morale, danno esistenziale, danni ...
PROCIDA MIRABELLI DI LAURO, ANTONINO
core  

Persona, vacuidad y primera persona

open access: yesRevista de Filosofía UCSC
This paper aims to examine the relationship between person and emptiness, its impact on Keiji Nishitani's thought, especially with his idea of ​​the first person. It also reflects on the problematic nature of the concept of reality in relation to the self, where reference is made to Descartes, Kant and Husserl and to some observations of philosophers ...
Jaime Montero, Elizabeth Duvanca
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Spare parts management: a comparison between (s,s) policy with delayed ordering and policy based on binomial distribution and total cost

open access: yes, 2013
Spare parts management is a critical issue for the companies due to the typical characteristics of this kind of items, high unit value, high level of technology, non-regular demand and specialized uses. Generally, this problem is faced with two different
PERSONA, ALESSANDRO   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Un retorno a la persona: la posible nueva cara del desarrollo

open access: yes, 2012
6 páginasIt is difficult to be optimistic about the results of the 2012 Earth Summit, Rio+20, since the good intentions expressed there do not by themselves give way to the changes that are necessary to make the planet we inhabit sustainable.
Gamboa Bernal, Gilberto A.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Autonomia della macchina e identità della persona

open access: yes, 2022
Il lavoro si propone di intercettare ed esplorare la nuova vulnerabilità della persona umana esposta al potere digitale: quello di chi detiene l’apparato tecnologico nella società dell’informazione contemporanea.
Raffaella Messinetti
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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