Results 41 to 50 of about 3,854,422 (185)

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Chronotype and Peripheral Clock Genes: Association With Frailty and Insomnia in Mexican Older Adults

AGING MEDICINE, EarlyView.
Chronotype, insomnia, frailty, and peripheral clock gene expression were evaluated in community‐dwelling older adults. Extreme morning chronotype was associated with lower odds of insomnia, whereas women showed higher odds of insomnia. Pre‐frail and frail participants exhibited lower peripheral clock gene expression patterns than robust individuals ...
Citlally E. Ortiz‐Vázquez, Paola Garcia‐delaTorre, Sergio Sánchez‐García, Lorena Aguilar‐Arnal, Lucía Mendoza‐Viveros   +4 more
wiley   +1 more source

A new level of technology is a new level of self-monitoring in the management of diabetes

Медицинский совет, 2015
The growing incidence of diabetes mellitus (DM) calls for adequate management of the disease through the successful use of blood glucose monitoring systems, or portable personal glucose meters (PGM).
O. V. Svetlova, I. V. Guryeva
doaj   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Using personal glucose meters and functional DNA sensors to quantify a variety of analytical targets [PDF]

Nature Chemistry, 2011
Portable, low-cost and quantitative detection of a broad range of targets at home and in the field has the potential to revolutionize medical diagnostics and environmental monitoring. Despite many years of research, very few such devices are commercially available.
Yu, Xiang, Yi, Lu
openaire   +2 more sources

Studies on the Nutritional, Functional, Textural, and Sensory Characteristics of Finger and Barnyard Millet‐Incorporated Nuggets

Food Chemistry International, EarlyView.
The graphic illustrates the development of nuggets traditionally known as “wari” prepared with whole green grams and composite flour barnyard millet var. (PRJ‐1) and finger millet var. (VL‐M‐380) in a 1:1 ratio. The addition of millet significantly improved the nutritional value of nuggets, providing higher levels of protein, carbohydrates, fiber ...
Payal Chauhan, Mahesh Gupta
wiley   +1 more source

Flexible wearable electronics for cardiovascular monitoring from surface signals to deep physiological insights

FlexMat, EarlyView.
This review organizes flexible wearable electronics for cardiovascular monitoring into four interconnected information layers: surface electrophysiology, hemodynamic sensing, vascular imaging, and biofluid biomarker analysis. This framework clarifies how electrical rhythm, vascular loading, structural and flow‐related features, and biochemical states ...
Qiao Chen, Hongwen Chen, Yuanyuan Li, Pingan Yang, Rui Li, Zhihao Zhou   +5 more
wiley   +1 more source

Giving New Uses to Glucose Meters: Detection of Prostate Cancer

, 2020
A sandwich genoassay for the detection of PCA3, a nucleic acid biomarker overexpressed in the urine of prostate cancer patients, has been developed by using the enzyme alkaline phosphatase (ALP) as a tracer of the hybrid generated onto the surface of ...
Noemí de-los-Santos-Álvarez, María Jesús Lobo-Castañón, Rebeca Miranda-Castro, Clara Abardía-Serrano   +3 more
core   +1 more source

Thermodynamic and Kinetic Studies of Glucose Mutarotation by Using a Portable Personal Blood Glucose Meter

, 2015
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)A thermodynamic and kinetic study of the mutarotation reaction of D-glucose in aqueous solution was carried out using a portable personal blood glucose meter.
Volpe, PLO, Perles, CE
core   +1 more source

Fabrication of flexible composite electrodes and their application in flexible supercapacitors for wearable electronic devices

FlexMat, EarlyView.
This review surveys current progress in composite flexible electrodes for flexible supercapacitors, emphasizing how structural engineering and material synergy enhance both mechanical compliance and electrochemical performance. It discusses fabrication strategies, emerging application scenarios, and ongoing challenges, offering updated insights that ...
Weikang Wang, Qing Liu, Ang Lv, Shuai Zhou, Chunlei Zhang, Luping Zhang, Liming Li, Weiwei Zhao, Yuchun Tang, Fei Huang   +9 more
wiley   +1 more source