Results 151 to 160 of about 1,120,114 (285)

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

People With Haemophilia as Data Coordinators: An Analysis of the Ethics and Feasibility of Self-Management With Personal Health Records. [PDF]

Haemophilia
Brands MR, Baas L, Driessens MH, Gouw SC, van der Graaf R, Meijer K, SYMPHONY consortium.   +6 more
europepmc   +1 more source

Wavy‐Interlocked Stretchable Triboelectric Nanogenerators Enhanced by Liquid Metal Microflowers for Self‐Powered Wearable Motion Monitoring

Advanced Science, EarlyView.
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu, Huimin Li, Hanmin Zeng, Yahui Meng, Yimeng He, Xinke Hu, Senfeng Zhao, Jianxun Zhang, Peiqiong Zhou, Kechao Zhou, Dou Zhang, Chris Bowen, Yan Zhang   +12 more
wiley   +1 more source

Development and internal validation of a prediction model for sleep apnea syndrome treated with continuous positive airway pressure based on claims and health checkup data linked to personal health records. [PDF]

Sleep Breath
Muraki T, Ueda T, Hasegawa C, Usui H, Koshimizu H, Ariyada K, Kusajima K, Tomita Y, Yanagisawa M, Iwagami M.   +9 more
europepmc   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

A Secure Personal Health Record Repository.

, 2012
Due to strict regulatory, ethic and legal issues, Electronic Health Record (EHR) systems have been mainly deployed in federated health care scenarios. This situation has been hindering the wide adoption of EHRs, contributing to delaying the establishment of a competitive market where contributions from different providers could take full advantage of ...
Pedrosa, Tiago, Lopes, Rui Pedro, Santos, João C., Costa, Carlos Manuel Azevedo, Oliveira, José Luís   +4 more
openaire   +1 more source

Adoption of Personal Health Records in Dutch Hospitals and Private Medical Clinics: Longitudinal Study. [PDF]

J Med Internet Res
van der Smissen D, Leenen-Brinkhuis C, Janssens KME, Porte PJ, van Assen MALM, Weggelaar-Jansen AM.   +5 more
europepmc   +1 more source

Utility, Value, and Benefits of Contemporary Personal Health Records: Integrative Review and Conceptual Synthesis. [PDF]

J Med Internet Res, 2021
Ruhi U, Chugh R.
europepmc   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

A systematic review of the effect of personal health records on patient activation. [PDF]

Digit Health
Osovskaya I, Blandford A, Potts HW.
europepmc   +1 more source