Results 41 to 50 of about 3,164,298 (286)

Understanding personal data as a space - learning from dataspaces to create linked personal data [PDF]

open access: yes, 2014
In this paper we argue that the space of personal data is a dataspace as defined by Franklin et al. We define a personal dataspace, as the space of all personal data belonging to a user, and we describe the logical components of the dataspace.
Dragan, Laura   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Preferred Distance in Human–Drone Interaction

open access: yesVision
In two augmented-reality experiments, we transferred the paradigm of interpersonal distance regulation to human–drone interaction. In the first experiment, we used a simple spherical drone model and explored how both hovering height and approach angle ...
Elisabeth Maria Wögerbauer   +3 more
doaj   +1 more source

A Short and Personal History of the Spitzer Space Telescope [PDF]

open access: yes, 2005
The Spitzer Space Telescope, born as the Shuttle Infrared Telescope Facility (SIRTF) and later the Space Infrared Telescope Facility (still SIRTF), was under discussion and development within NASA and the scientific community for more than 30 years prior
Werner, Michael
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

“Notorious RBG”: A conversation with United States Supreme Court Justice Ruth Bader Ginsburg [PDF]

open access: yes, 2017
On February 2, 2016, Prof. Ruth Rubio-Marín, Chair of Constitutional and Comparative Public Law at the European University Institute (EUI), interviewed the U.S. Supreme Court Associate Justice Ruth Bader Ginsburg.
Rubio-Marín, Ruth
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

The shape of personal space [PDF]

open access: yesActa Psychologica, 2019
The notion of a personal space surrounding one's ego-center is time-honored. However, few attempts have been made to measure the shape of this space. With increasing use of virtual environments, the question has arisen if real-world aspects, such as gender-effects or the shape of personal space, translate to virtual setups. We conducted two experiments,
Heiko Hecht   +3 more
openaire   +2 more sources

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