Results 51 to 60 of about 910,809 (261)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Psicologia: Reflexão e Crítica, 2006 Valores laborais são princípios ou metas, hierarquicamente organizadas, que as pessoas buscam e que guiam a sua vida no trabalho. A família, a escola e a experiência de trabalho são apontadas como as variáveis mais influentes na formação dos valores ...
Juliana Barreiros Porto, Alvaro Tamayo
doaj +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
The Civil Law Regime Governing Immaterial Values in the Russian Federation
RUDN Journal of LawThe increasing importance of immaterial values necessitates further legal investigation into their significance and protection. This article addresses two theoretical problems identified by the author, aiming to resolve them. First, it considers the role
Yuri E. Monastyrsky
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Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Professionalism in medical students: what actually makes a difference? [Letter]
Advances in Medical Education and Practice, 2019 Kiran Pillai, Muhammed Kermali, Ahsan Rashid Faculty of Medicine, Medical Student at St George’s, University of London, London, UK We read with great interest the study by Selic et al1 regarding the influence of personal values and ...
Pillai K, Kermali M, Rashid A
doaj
Revista Gestão Universitária na América Latina, 2018 The percentage of the Brazilian population with higher education is still low, even when it's compared with other Latin American countries. Thus, it's relevant to understand the influences and motivations of high school students to enter higher education.
Fernando Lopes Coutinho +2 more
doaj +1 more source