Results 41 to 50 of about 733,815 (225)

Neobacillus driksii sp. nov. isolated from a Mars 2020 spacecraft assembly facility and genomic potential for lasso peptide production in Neobacillus

Microbiology Spectrum
During microbial surveillance of the Mars 2020 spacecraft assembly facility, two novel bacterial strains, potentially capable of producing lasso peptides, were identified.
Asif Hameed, Francesca McDonagh, Pratyay Sengupta, Georgios Miliotis, Shobhan Karthick Muthamilselvi Sivabalan, Lukasz Szydlowski, Anna Simpson, Nitin Kumar Singh, Punchappady Devasya Rekha, Karthik Raman, Kasthuri Venkateswaran   +10 more
doaj   +1 more source

Fecal Virome Transplantation in Human Disease and Livestock Production: Evidence, Mechanisms, and Translational Challenges

Animal Research and One Health, EarlyView.
Fecal virome transplantation may reshape bacterial communities and host responses while reducing viable bacterial transfer. Preclinical evidence suggests biological activity, but human efficacy remains uncertain, and translation requires product standardization, causal validation, donor–recipient matching, and rigorous biosafety assessment.
Luanyang Shi, Yongjuan Guan, Guanxiang Liang   +2 more
wiley   +1 more source

Single‐subject designs in character education: Methods for rigorous, contextual, and practitioner‐led research

British Educational Research Journal, EarlyView.
Abstract Character education research is often constrained by blunt methodological tools. Surveys capture breadth without depth; case studies offer richness but lack replicability; and randomised controlled trials (RCTs), though indispensable at the policy level, are costly, disruptive and ill‐suited to everyday practice with individual pupils.
Shane McLoughlin
wiley   +1 more source

Exploring interactions of the dimensions of agency through the experiences of aspiring school leaders in Scotland, UK

British Educational Research Journal, EarlyView.
Abstract Agency has increasingly become a central concept in educational leadership research, yet its application to those preparing to enter school leadership roles remains underexplored. Drawing on the conceptual framework of the ecological approach to teacher agency, we explored how and in what ways aspiring school leaders in Scotland (n = 21 ...
Romina Madrid Miranda, Andrea Priestley, Elizabeth A. C. Rushton   +2 more
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Significance of flavonoids targeting PI3K/Akt/HIF-1α signaling pathway in therapy-resistant cancer cells – A potential contribution to the predictive, preventive, and personalized medicine

Journal of Advanced Research
Background: Cancer management faces multiple obstacles, including resistance to current therapeutic approaches. In the face of challenging microenvironments, cancer cells adapt metabolically to maintain their supply of energy and precursor molecules for ...
Alena Mazurakova, Lenka Koklesova, Sandra Hurta Csizmár, Marek Samec, Aranka Brockmueller, Miroslava Šudomová, Kamil Biringer, Erik Kudela, Martin Pec, Samson Mathews Samuel, Monika Kassayova, Sherif T.S. Hassan, Karel Smejkal, Mehdi Shakibaei, Dietrich Büsselberg, Luciano Saso, Peter Kubatka, Olga Golubnitschaja   +17 more
doaj   +1 more source

Efficacy and safety of the Patient Empowerment through Predictive Personalised Decision Support (PEPPER) system: an open-label randomised controlled trial [Pòster]

, 2020
Pòster de congrés presentat a: ATTD 2020 - 13th International Conference on Advanced Technologies & Treatments for Diabetes”, celebrat a Madrid del 19 al 22 de febrer de 2020PEPPER (Patient Empowerment through Predictive PERsonalised decision support) is
Martin, Clare, Fernández-Balsells, Mercè, Avari, Parizad, López Ibáñez, Beatriz, Reddy, Monika, Fernández-Real Lemos, José Manuel, Nita, Lucian, Herrero i Viñas, Pau, Massana i Raurich, Joaquim, Wos, Marzena, Thomas, Maria, Jugnee, Narvada, Oliver, Nick, Leal Moncada, Yenny Teresa   +13 more
core   +1 more source

Circular Economy in the Healthcare Industry: Developing a Circularity Assessment Tool for Complex Medical Devices

Business Strategy and the Environment, EarlyView.
ABSTRACT As the circular economy transition gains traction in the healthcare sector, extending the lifespan of complex medical devices has become a key priority, given their high cost and the challenges associated with their technological sophistication.
Tetiana Shevchenko, Lauren Durivault, Meisam Ranjbari, Zahra Shams Esfandabadi, Bernard Yannou, Robert Heidsieck, Michael Saidani, Ghada Bouillass   +7 more
wiley   +1 more source

Experiencing Shakespeare: multimodal communication and multisensory engagement in Stratford-upon-Avon

Актуальні проблеми української лінгвістики: теорія і практика
The article examines how Shakespearean heritage institutions in Stratford-upon-Avon are redefining contemporary museum exhibition practices through immersive, multimodal and multisensorial storytelling.
Julia Biliuk
doaj   +1 more source

Personalised cancer medicine

, 2021
What does it mean to personalise cancer medicine? Personalised cancer medicine explores this question by foregrounding the experiences of patients, carers and practitioners in the UK. Drawing on an ethnographic study of cancer research and care, we trace
Kerr, Anne, Ross, Emily, Swallow, Julia, Key Chekar, Choon, Cunningham-Burley, Sarah   +4 more
core