Results 81 to 90 of about 4,537 (296)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Reappreciating Patient Autonomy in Light of Ratzingerian Christian Personalism
This commentary proposes that Christian personalism could complement in one way a principlism approach to healthcare. Such a proposal is consistent with the argument of Pellegrino that the concept of personhood is integral to the Christian healthcare ...
Teofilo Giovan S. Pugeda
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
The citizen: an Ubuntu personalism conception [PDF]
In this thesis, I argue for an Ubuntu personalism conception of the citizen as a foundationalist account of a grounding for the pluralist political arrangement based on human rights.
Seale, Wade
core
The practical wisdom of personalism
, 2010 PurposeCurrent mainstream management theory is based on incomplete assumptions regarding the nature of human beings and human action, leading to damaging practical results.
Helen Alford
core +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Review of Robert McNamara, The Personalism of Edith Stein: A Synthesis of Thomism and Phenomenology
Journal of Moral TheologyReview of Robert McNamara, _The Personalism of Edith Stein: A Synthesis of Thomism and ...
Catherine Moon
doaj +1 more source
Personal Participation in the Thomistic Account of Natural Law
Studia Gilsoniana, 2018 The author seeks to show how participation serves as a focal point of a Thomistic personalist account of natural law. While Aquinas himself does not invoke the concept of person in his account of natural law, the author argues that participation can and ...
Catherine Peters
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source