Results 91 to 100 of about 2,335,934 (355)

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock, Jihyun Park, Dae‐Gyu Jang, Bangyao Zhao, Samuel J. Teener, Ian F. Webber‐Davis, Lili Zhao, Eva L. Feldman, Stephen A. Goutman   +8 more
wiley   +1 more source

Normal and Abnormal Personality Traits are Associated with Marital Satisfaction for both Men and Women: An Actor–Partner Interdependence Model Analysis [PDF]

, 2010
Research has demonstrated associations between relationship satisfaction and personality traits. Using the Actor–Partner Interdependence Model, we explored associations between self-reported relationship satisfaction in couples (n = 118) and various ...
Durbin, C. Emily, Knobloch-Fedders, Lynne M., Saigal, Seema D., Stroud, Catherine B.   +3 more
core   +1 more source

The relationship between recalled self-esteem as a child and current levels of professional burnout among Anglican clergy in England [PDF]

, 2010
This study links and tests three strands of theory concerned with explaining individual differences in levels of professional burnout in general and among religious professionals in particular. These three strands concern the significance of current self-
Francis, Leslie J., Robbins, Mandy, Rolph, Jenny, Rolph, P., Turton, Douglas W.   +4 more
core   +1 more source

Person as Scientist, Person as Moralist [PDF]

Behavioral and Brain Sciences, 2010
AbstractIt has often been suggested that people's ordinary capacities for understanding the world make use of much the same methods one might find in a formal scientific investigation. A series of recent experimental results offer a challenge to this widely-held view, suggesting that people'smoraljudgments can actually influence the intuitions they ...
openaire   +3 more sources

Remaining Burden of Spinal Muscular Atrophy Among Treated Patients: A Survey of Patients and Caregivers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons, Natalie Land, Melissa Culhane Maravic, Claire Cagle, Amal Jamaleddine, Hemal Shah, Thomas Brown, Christabella Cherubino, Mouhamed Gueye   +8 more
wiley   +1 more source

The effect of slow breathing in regulating anxiety

Scientific Reports
Anxiety is an interactive disorder of the mind and body, characterized by excessive worry about uncertain future events and a dysfunction of the autonomic nervous system.
Qian Luo, Xianrui Li, Jia Zhao, Qiu Jiang, Dongtao Wei   +4 more
doaj   +1 more source

The Moderating Role of Vertical Collectivism in South-Korean Adolescents’ Perceptions of and Responses to Autonomy-Supportive and Controlling Parenting

Frontiers in Psychology, 2018
Research increasingly demonstrates that associations between autonomy-relevant parenting and adolescent adjustment generalize across cultures. Yet, there is still an ongoing debate about the role of culture in these effects of autonomy-relevant parenting.
Bart Soenens, Seong-Yeon Park, Elien Mabbe, Maarten Vansteenkiste, Beiwen Chen, Stijn Van Petegem, Katrijn Brenning   +6 more
doaj   +1 more source

Do personality states predict momentary task performance? The moderating role of personality variability [PDF]

, 2015
We investigated how state neuroticism and state conscientiousness related to momentary task performance and tested whether these relationships were affected by the extent to which a person varies in his level of state neuroticism/conscientiousness across
De Fruyt, Filip, Debusscher, Jonas, Hofmans, Joeri   +2 more
core   +2 more sources

Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck, Jan Voth, Noëmi Gmahl, Konstantin Jendretzky, Niklas Huntemann, Noah M. Werner, Linea Schmidt, Menekse Oeztuerk, Paula Quint, Christina B. Schroeter, Hans Peter Hartung, Thomas Skripuletz, Gerd Meyer zu Hörste, Tobias Ruck, Sven G. Meuth, Marc Pawlitzki   +15 more
wiley   +1 more source

Psychological intervention in patients with central sensitization syndromes and comorbid psychosocial trauma: a systematic review and meta-analysis

Scientific Reports
The co-occurrence of central sensitization syndromes (CSS) and post-traumatic symptoms (PTSS) or post-traumatic stress disorder (PTSD) exacerbates impairment, and treatment is unsatisfactory in many cases.
Coralie Maire, Ana I. Sánchez, José M. Ventura-Lucena, Elena Miró, M. Pilar Martínez   +4 more
doaj   +1 more source