Results 41 to 50 of about 3,503,623 (355)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Supporting parents with borderline personality disorder through a parenting group intervention: a randomized controlled trial

Borderline Personality Disorder and Emotion Dysregulation
Background There is a need for a parenting intervention that specifically addresses the concerns for parents with borderline personality disorder (BPD) due to the challenges that these parents experience and the stigma that surrounds parenting with BPD ...
Brin F. S. Grenyer, Charlotte C. van Schie, Dianna R. Bartsch, Laura Cooke-O’Connor, Dominic Kleinig, Kayla R. Steele, Cathy McLeod Everitt   +6 more
doaj   +1 more source

The Cross-Sectional and Longitudinal Associations between Household Chaos, Perceived Stress, and Borderline Personality Disorder Features in Outpatient Youth

Youth
This study examined how household chaos, perceived stress, and their interaction are related to borderline personality disorder (BPD) features both cross-sectionally and at 1-year follow-up in outpatient youth. Data from 143 youth were analysed.
Anouk Aleva, Geerte de Boois, Christel J. Hessels, Odilia M. Laceulle   +3 more
doaj   +1 more source

Borderline Personality Disorder [PDF]

Canadian Medical Association Journal, 2005
Abstract Borderline personality disorder (BPD) describes a clinical syndrome commonly seen in practice (Zimmerman, Rothschild, & Chelminski, 2005). The most characteristic symptom is chronic suicidality (Paris, 2002), with recurrent overdoses and selfmutilation.
openaire   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Comparison of Cognitive Behavioral Therapy and Cognitive Behavioral Group Therapy in the Treatment of Avoidant Personality Disorder

Psikiyatride Güncel Yaklaşımlar, 2023
The primary aim of this study is to compile studies on cognitive behavioral therapy method in the treatment of avoidant personality disorder and present their data.
Esra Amet, Tuğba Hüseyin Muhtar, Fatma Nur Özçelik   +2 more
doaj   +1 more source

Borderline Personality Disorder

Focus, 2011
Recent research findings have contributed to an improved understanding and treatment of borderline personality disorder. This disorder is characterised by severe functional impairments, a high risk of suicide, a negative effect on the course of depressive disorders, extensive use of treatment, and high costs to society.
Leichsenring, Falk, Leibing, Eric, Kruse, Johannes, New, Antonia S., Leweke, Frank   +4 more
openaire   +3 more sources

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Attitude of Treating Psychiatrist Towards Personality Disorder

Journal of Nepal Health Research Council, 2018
Background: Worldwide mental health professionals have negative attitude towards personality disorder. Aim of this study was to assess the attitudes toward personality disorder among Nepalese psychiatrists.
Pratikchya Tulachan, Manisha Chapagain, Saraswati Dhungana, Sagun Ballav Pant, Saroj Prasad Ojha   +4 more
doaj   +1 more source