Results 21 to 30 of about 50,358 (223)

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

Identifying and Manipulating the Personality Traits of Language Models [PDF]

arXiv, 2022
Psychology research has long explored aspects of human personality such as extroversion, agreeableness and emotional stability. Categorizations like the `Big Five' personality traits are commonly used to assess and diagnose personality types. In this work, we explore the question of whether the perceived personality in language models is exhibited ...
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Learning Person-specific Network Representation for Apparent Personality Traits Recognition [PDF]

arXiv, 2023
Recent studies show that apparent personality traits can be reflected from human facial behavior dynamics. However, most existing methods can only encode single-scale short-term facial behaviors in the latent features for personality recognition. In this paper, we propose to recognize apparent personality recognition approach which first trains a ...
arxiv  

Integrating Personality Structure, Personality Process, and Personality Development [PDF]

European Journal of Personality, 2017
In this target article, we argue that personality processes, personality structure, and personality development have to be understood and investigated in integrated ways in order to provide comprehensive responses to the key questions of personality psychology.
Cornelia Wrzus, Elena Kurzius, Marco Perugini, Anna Baumert, Anna Baumert, Jaap J. A. Denissen, Manfred Schmitt, Giulio Costantini, Lynn C. Miller, Eranda Jayawickreme, Michael D. Robinson, Colin MacLeod, William Fleeson, Gabriela Blum, Brent W. Roberts, Brent W. Roberts, Stephen J. Read, Wendy Johnson, Peter Borkenau, Dustin Wood, Ben Grafton   +20 more
openaire   +3 more sources

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Third person enforcement in a prisoner's dilemma game [PDF]

arXiv, 2019
We theoretically study the effect of a third person enforcement on a one-shot prisoner's dilemma game played by two persons, with whom the third person plays repeated prisoner's dilemma games. We find that the possibility of the third person's future punishment causes them to cooperate in the one-shot game.
arxiv  

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Personalities of the Personality of Recidivists [PDF]

Bulletin of Science and Practice, 2019
The article discusses the personality of a recidivist. The specifics of the influence of the criminal subculture on crime is investigated, its especially socially dangerous characteristics are revealed. The author of the proposed correction of legislative acts was the appointment of punishment, taking into account the personal qualities of the offender.
openaire   +2 more sources