Results 101 to 110 of about 576,044 (343)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Developing products for personalized medicine: NIH Research Tools Policy applications [PDF]

, 2004
Ranjan Gupta, JP Kim, Jack Spiegel, Steven M. Ferguson   +3 more
openalex   +1 more source

"Knowledge-based (personalized) medicine” instead of "evidence-based (cohort) medicine” [PDF]

, 2017
No abstract ...
Hunziker, Patrick
core  

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Personalized medicine industry model development

Management : Journal of Contemporary Management Issues, 2017
Health care is a growing business, but its trajectory patterns are hard to decipher at the moment. This paper provides a short overview of issues important for developing business models for the personalized medicine sector (PM).
Marija Kaštelan Mrak, Nada Bodiroga Vukobrat, Danijela Sokolić   +2 more
doaj   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Embracing personalized medicine in dentistry

Journal of Pharmacy and Bioallied Sciences, 2019
Aim: The aim of this systematic review was to evaluate the number of articles in the area of personalized medicine specific to dentistry. Materials and Methods: Electronic search using three databases was performed using PubMed, Embase, and Scopus search.
Manchala Sesha Reddy, Shishir Ram Shetty, Venkataramana Vannala   +2 more
doaj   +1 more source

432: Informed Consent and Subject Motivation to Participate in a Large, Population-Based Genomics Study: The Marshfield Clinic Personalized Medicine Research Project [PDF]

, 2005
Catherine A. McCarty, Arun Nair, Diane M. Austin, Philip F. Giampietro   +3 more
openalex   +1 more source

Privacy and Accountability in Black-Box Medicine [PDF]

, 2016
Black-box medicine—the use of big data and sophisticated machine learning techniques for health-care applications—could be the future of personalized medicine.
Ford, Roger Allan, Price, W. Nicholson, II   +1 more
core   +3 more sources