Results 81 to 90 of about 4,097,121 (312)

Research and innovation in personalized medicine: a descriptive synthesis of actors in the EU and China

open access: yes, 2023
Aim: Research and innovation (R&I) actors are fundamental in shortening the translational gap of personalized medicine in health systems. In the context of the ‘Integrating China in the International Consortium for Personalized Medicine’ project, we ...
Ricciardi, Walter   +14 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Personalized (laboratory) medicine: a bridge to the future.

open access: yes, 2013
Personalized (laboratory) medicine: a bridge to the ...
PLEBANI, MARIO   +3 more
core   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

Personalized medicine: moving from simple theory to daily practice.

open access: yes, 2015
Personalized medicine: moving from simple theory to daily ...
Lippi G, PLEBANI, MARIO, LIPPI, Giuseppe
core   +1 more source

Implementing personalized medicine with asymmetric information on prevalence rates [PDF]

open access: yes, 2016
Although personalized medicine is becoming the new paradigm to manage some diseases, the economics of personalized medicine have only focused on assessing the efficiency of specific treatments, lacking a theoretical framework analyzing the interactions ...
Carmelo A. Juárez-Castelló   +11 more
core   +2 more sources

Personalized Medicine in Europe

open access: yesClinical and Translational Science, 2017
Personalised medicine is a promising new concept for dealing with challenges of health and health systems. With the launch of the International Consortium of Personalised Medicine, which brings together health research funders and policy making organisations, European countries aim to coordinate research and health policy to advance the implementation ...
Nimmesgern, E   +2 more
openaire   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Priorities for Personalized Medicine

open access: yes, 2008
Advances in genomics and molecular biology have opened new possibilities for the field of personalized medicine, promising improvements in patient care, disease prevention, and possibly lower health care costs.
Subcommittee on Personalized Medicine   +1 more
core  

Personalized Medicine: Worth Its Cost? [PDF]

open access: yes, 2015
Already stretched health care systems face a panoply of challenges, including a high and increasing number of patients with chronic conditions, expensive and rising costs of treatment, and stagnant economies.
Carrera, Percivil M.
core   +1 more source

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