Results 201 to 210 of about 627,364 (295)

G protein-coupled receptor digital twins for precision and personalized medicine. [PDF]

Comput Struct Biotechnol J
Boeringer T, Pardo M, Craig CJ, Maudsley S.   +3 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

P578: Using the large-language model GPT4 to programmatically determine functional evidence supporting or refuting variant pathogenicity from literature*

Genetics in Medicine Open
Matthew Lebo, Kalotina Machini, Pranav Sriraman, Jiyeon Shin, Emma Henricks, Carly Mailly, Michael Oates, Samuel Aronson   +7 more
doaj   +1 more source

Genes, Drugs, and Personalized Medicine-The DNA of a Pharmacogenomics Curriculum. [PDF]

Med Sci Educ
Chang LF, Sreedhar R.
europepmc   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Precision/Personalized medicine in cancer

Biomedical Research Journal, 2015
Dhananjaya Saranath, Aparna Khanna
doaj   +1 more source

Personalized medicine strategy for MPNSTs: using precision oncology on PDOX models to inform tumor boards. [PDF]

J Transl Med
Ortega-Bertran S, Fernández-Rodríguez J, Magallón-Lorenz M, Creus-Bachiller E, Uriarte-Arrazola I, Mazuelas H, Garraus M, Carrió M, Gel B, Rovira C, Alvarez M, Villanueva A, Castaneda A, Salvador H, Serra E, Lázaro C.   +15 more
europepmc   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Creatine as a mitochondrial theranostic in predictive, preventive, and personalized medicine. [PDF]

EPMA J
Ostojic SM, Rátgéber L.
europepmc   +1 more source