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Nanotheranostics for personalized medicine
Advanced Drug Delivery Reviews, 2012The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past, as versatile strategy for selective drug delivery and diagnostic purposes. The already encouraging results obtained with monofunctional nanomedicines have directed the efforts of the scientists towards the creation of ...
Simona, Mura, Patrick, Couvreur
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Personalized precision medicine
Bio-Algorithms and Med-Systems, 2019Abstract Along with the development of modern science, medical knowledge and therapy become more and more precise and personal as a consequence. Genetics and immunology participate in the progress in particular. They open the way to molecular knowledge, allowing precise interpretation of pathology in individual cases followed by finding ...
Leszek Konieczny, Irena Roterman
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Pharmacometabonomics and personalized medicine
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2013Background Pharmacometabonomics is a new branch of science, first described in 2006 and defined as ‘the prediction of the effects of a drug on the basis of a mathematical model of pre-dose metabolite profiles’. Pharmacometabonomics has been used to predict drug metabolism, pharmacokinetics (PK), drug safety and ...
Everett, Jeremy +2 more
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Personalized Medicine: A Personal View
Clinical Pharmacology & Therapeutics, 2012Personalized medicine is a strategy to prevent, diagnose, and treat disease so as to achieve an optimal result for the individual. The sequencing of the human genome and other technological advances have revealed the extent of genetic diversity and the relative contribution of genetic and nongenetic factors to human health, disease, and drug response ...
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Pharmacogenetics and Personalized Medicine
2017Recent advances in the comprehension of pathogenic mechanisms of human diseases have brought the researchers to the discovery of putative pharmacological targets and the subsequent development of the so-called targeted drugs. In order to maximize their efficacy, as well as that of the other drugs, it is imperative to identify those patients that are ...
Di Paolo, Antonello +3 more
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Genomics and personalized medicine
International Journal of Pharmaceutics, 2011The role of genomics in personalized medicine continues to undergo profound changes, in step with dramatic technological advances. Ability to sequence the entire human genome with relative ease raises expectations that we can use an individual's complete genomic blueprint to understand disease risk and predicting therapy outcomes, thereby, optimizing ...
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The path to personalized medicine
Current Opinion in Chemical Biology, 2002Advances in personalized medicine, or the use of an individual's molecular profile to direct the practice of medicine, have been greatly enabled through human genome research. This research is leading to the identification of a range of molecular markers for predisposition testing, disease screening and prognostic assessment, as well as markers used to
Joanne M, Meyer, Geoffrey S, Ginsburg
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Biobanking for Personalized Medicine
2015A biobank is an entity that collects, processes, stores, and distributes biospecimens and relevant data for use in basic, translational, and clinical research. Biobanking of high-quality human biospecimens such as tissue, blood and other bodily fluids along with associated patient clinical information provides a fundamental scientific infrastructure ...
Angen, Liu, Kai, Pollard
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Nanobiotechnology and Personalized Medicine
2011This chapter will start with a definition and scope of personalized medicine and describe how various nanobiotechnologies will contribute to its development. Nanodiagnostics and its combination with therapeutics as well as nanoparticle-based drug delivery will play an important role.
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