Results 111 to 120 of about 2,419,473 (338)
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Íconos, 2020 Introduction to dossier Disappearances of people in the globalized world: Challenges from Latin ...
Carolina Robledo Silvestre +1 more
doaj
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
“yellow crowfoot in the pond,/not lotus, not lily”: Mapping the River, Mapping Voices [PDF]
, 2016 This paper examines the prosody of Chin’s eponymous poem, The Phoenix Gone, The Terrace Empty, through an eco-critical lens. While it does not dismiss the hybrid cultural influences of the poem, it focuses on the ways the non-human agents, or the ...
Rader, Pamela J.
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Crecimiento empresarial: personas y tecnología en la nueva economía
Revista Empresa y Humanismo, 2000 La brusca irrupción de Internet y de las nuevas tecnologías en la empresa, y la globalización de los mercados de capitales han planteado a las empresas un nuevo reto, hasta ahora, menos prioritario: la necesidad de encontrar nuevas vías para el ...
Jordi Canals
doaj
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Learning Health SystemsIntroduction Learning health networks (LHNs) improve clinical outcomes by applying core tenets of continuous quality improvements (QI) to reach community‐defined outcomes, data‐sharing, and empowered interdisciplinary teams including patients and ...
Dylan J. Cooper +20 more
doaj +1 more source
The organizational design of nonprofits for people with disabilities [PDF]
, 2009 Utilizando información obtenida de los directivos de 105 pequeñas organizaciones sin fines de lucro españolas que, en el año 2007, se dedicaban a la prestación de servicios a personas con discapacidad, hemos analizado como el diseño organizativo –en ...
Cossío Silva, Francisco José (Coordinador) +2 more
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