Results 131 to 140 of about 2,796,276 (306)

Malos tratos a personas mayores [PDF]

open access: yes, 2012
[Resumen] El problema de los malos tratos a las personas mayores existe en casi todas las sociedades. Aunque en la mayoría de estas no haya suficiente información sobre los mismos, no implica que no exista este tipo de violencia pero, la hay y se produce
Pita Díaz, Rosario
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Persona Journey Mapping to Drive Equity During an LMS Transition

open access: yesIssues and Trends in Learning Technologies
Technology systems that support learning–such as Learning Management Systems, or LMS’s–can change frequently in higher education. This often creates significant challenges for faculty-support staff during a transition–or migration–period.
Kam Moi Lee   +2 more
doaj   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

La resiliencia en los profesionales de extinción de incendios forestales:

open access: yesBiodiversidade Brasileira, 2019
Debido a las características propias del trabajo en extinción de incendios forestales, los/las profesionales pueden verse expuestos a experimentar situaciones de alto impacto psicológico y emocional al verse involucrados en un accidente o incidencia ...
Elena Hernandez Paredes   +2 more
doaj  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

'Surviving the Wilds of Academia': Personas Depicting Early-Career Engineering Education Scholars Role Crafting to Achieve Their Goals

open access: yesStudies in Engineering Education
Background: The increase in doctoral programs and certifications in the area of engineering education has led to an increase in Engineering Education Scholars (EES) on the job market.
Cheryl A. Bodnar   +5 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

La naturaleza del sujeto y el argumento de la unidad

open access: yesCrítica, 2019
En el presente trabajo examino diversas respuestas a la pregunta formulada por Descartes ¿Qué soy yo? Sugiero que, aunque la propuesta según la cual soy idéntico a mi organismo humano o a alguna parte del mismo (la tesis adoptada por los materialistas ...
Adrián Sampedro
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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