Results 141 to 150 of about 60,293 (261)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Experiences of older people in Long-Term Care Institutions in light of the theory of Liquid Modernity. [PDF]

Rev Esc Enferm USP
Oliveira MA, Otani MAP, Vernasque JRDS, Napoles JN, Herzog A, Marin MJS.   +5 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

[Ageism in health care and suicide risk in older adults: a challenge for public health in Latin AmericaIdadismo no âmbito da saúde e risco de suicídio em pessoas idosas: um desafio para a saúde pública na América Latina]. [PDF]

Rev Panam Salud Publica
Bozanic A, León T, Acevedo F, de la Maza E, Ulloa P.   +4 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

201 Implementation of the neurodevelopment and early intervention unit at the association for people with cerebral palsy (APAC)

BMJ Paediatrics Open
Ernesto Alarcón Cabrera, Verónica Joomayra Quintana Vega   +1 more
doaj   +1 more source

[Multicomponent exercise for people at high risk of frailty in the local context]. [PDF]

Aten Primaria
Simó Sanz C, Gil Ramos S, Moncada MD.
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Tailored personas for anticipatory grief management among primary family caregivers of patients with advanced lung cancer in China: a qualitative study. [PDF]

Sci Rep
Liu X, Jiang N, Yan H, Li J, Ma D, Wang W, Xie Y, Wang L, Ning L.   +8 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source