Results 161 to 170 of about 2,666,075 (354)

Decir la "persona" según Escoto (un intento de interpretación) [PDF]

, 2007
Isidoro Guzmán Manzano Rodríguez
openalex  

La persona humana y su formación en Antonio Millán-Puelles Mauricio Bicocca (2011). Pamplona: EUNSA.

, 2014
Ceferino P. D. Muñoz
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

La naturaleza del sujeto y el argumento de la unidad

Crítica, 2019
En el presente trabajo examino diversas respuestas a la pregunta formulada por Descartes ¿Qué soy yo? Sugiero que, aunque la propuesta según la cual soy idéntico a mi organismo humano o a alguna parte del mismo (la tesis adoptada por los materialistas ...
Adrián Sampedro
doaj  

Perspectivas y experiencias del COVID 19 desde las personas migrantes, representantes territoriales y de organizaciones sociales. La relevancia del abordaje sociosanitario

, 2022
Andrea Avaria, Sonia Brito, Lorena Basualto Porra, Rodrigo Azócar González, Claudia Estefani Laredes Flores   +4 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Semiotica per campagne di digital marketing. Alcune proposte operative

Ocula
This work is part of the extensive series of semiotic studies that, from the late 1980s to the present, have dialogued with the most diverse areas of marketing, up to the most recent digital marketing.
Giovanna Cosenza
doaj  

Normas para la protección y cuidado de personas ante la pandemia COVID-19 [PDF]

, 2020
Reynaldo Michel-Aceves, Manuel Gil-Vargas, Francisco Paredes-Fernández, Guillermo Yanowsky Reyes, Alfredo Vigueras-Rendón, Alicia Elizabeth Robledo‐Galván, Roberto Guillermo Calva-y Rodríguez   +6 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Empathy mapping and hybrid persona creation: Understanding older adults' needs in technology design for ageing in place. [PDF]

Comput Struct Biotechnol J
Kastl A.
europepmc   +1 more source